Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Evaluation of field-in-field, three-field, and four-field techniques for treatment planning of radiotherapy of pancreatic cancer

Fri Mar 29 15:09:53 2024

(2022) Evaluation of field-in-field, three-field, and four-field techniques for treatment planning of radiotherapy of pancreatic cancer. Journal of Cancer Research and Therapeutics. pp. 190-199. ISSN 0973-1482

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Abstract

Background: Pancreatic adenocarcinoma is a lethal condition with poor outcomes by various treatment modalities and an increasing incidence. Aim: The aim of this study is to evaluate the advantages of field-in-field (FIF) versus three-field and four-field radiation treatment planning techniques in three-dimensional treatment of patients with pancreatic cancer. Materials and Methods: The evaluations of these planning techniques were performed in terms of physical and biological criteria. Radiotherapy treatment data of 20 patients with pancreatic cancer were selected and evaluated for FIF, three-field, and four-field treatment techniques. The patients were treated by 6 MV photon beam of a medical linac, and these three treatment planning techniques were evaluated for all the 20 patients. The plans were compared based on dose distribution in the target volume, monitor unit (MU), and dose to organs at risk (OARs).Results: The results have shown that, with assuming the same prescribed dose to planned target volume, FIF plans have some advantages over three-field and four-field treatment plans, based on MU values, V-20 Gy in the right lung, V-20 Gy in the left lung, D-mean in the left kidney, D-mean in the liver, and D-mean in the spinal cord. Based on the obtained results, the use of FIF technique reduces MUs compared to the three-field and four-field techniques. Conclusion: Having a less MU for performing treatment reduces scattered radiation and therefore reduces the risk of secondary cancer in normal tissues. In addition, the use of FIF technique has advantage of less radiation dose to some OARs.

Item Type: Article
Creators:
CreatorsEmail
Pursamimi, M.UNSPECIFIED
Ghorbani, M.UNSPECIFIED
Parwaie, W.UNSPECIFIED
Shakeri, A.UNSPECIFIED
Meigooni, A. S.UNSPECIFIED
Keywords: Field-in-field four-field pancreatic cancer radiotherapy three-field treatment planning 3-dimensional conformal radiotherapy modulated radiation-therapy prostate-cancer dose distribution plans imrt histograms carcinoma photon beams Oncology
Divisions:
Page Range: pp. 190-199
Journal or Publication Title: Journal of Cancer Research and Therapeutics
Journal Index: ISI
Volume: 18
Number: 1
Identification Number: https://doi.org/10.4103/jcrt.JCRT₁₈₁₂₀
ISSN: 0973-1482
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/4015

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