(2005) Prevalence of Clostridium difficile- associated diarrhea in hospitalized patients with nosocomial diarrhea. Iranian Journal of Public Health. pp. 67-72. ISSN 22516085 (ISSN)
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Abstract
Clostridium difficile is a frequently identified cause of nosocomial gastrointestinal disease. It has been proved to be a causative agent in antibiotic-associated, diarrhea, antibiotic-associated colitis, and pseudomembraneous colitis. This study was aimed to determine the prevalence of C.difficile- associated diarrhea in hospitalized patients with nosocomial diarrhea. The 942 hospitalized patients stool samples with nosocomial diarrhea were collected at three hospitals in Tehran from Dec 2002 to Feb 2004.All the stool samples were cultured and in 97 (prevalence: 10.9) samples grew C.difficile that 57 (prevalence: 6.1) isolates were toxigenic by cytotoxicity assay and so 57 patients had C.difficile- associated diarrhea. Results of statistical analysis showed significant difference between the rate of C.difficile associated diarrhea and the patients ages (P<0.05).
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| Keywords: | Antibiotic-associated diarrhea Cytotoxicity assay Iran Nosocomial diarrhea Toxigenic Clostridium difficile aminoglycoside antibiotic agent amoxicillin ampicillin cephalosporin derivative clindamycin penicillin G quinoline derived antiinfective agent tetracycline derivative adolescent adult article bacterium identification bacterium isolation child Clostridium difficile controlled study diarrhea disease association feces analysis female gastrointestinal infection geographic distribution hospital infection hospital patient human infant major clinical study male population distribution prevalence statistical analysis statistical significance | ||||||||||||||||||
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| Page Range: | pp. 67-72 | ||||||||||||||||||
| Journal or Publication Title: | Iranian Journal of Public Health | ||||||||||||||||||
| Journal Index: | Scopus | ||||||||||||||||||
| Volume: | 34 | ||||||||||||||||||
| Number: | 4 | ||||||||||||||||||
| ISSN: | 22516085 (ISSN) | ||||||||||||||||||
| Depositing User: | مهندس مهدی شریفی | ||||||||||||||||||
| URI: | http://eprints.medilam.ac.ir/id/eprint/1691 |
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