Abstract

Introduction: Menopause is a permanent and important event in women life that the time of its creation is influenced by several factors. In this period due to hormonal changes, women are prone to cardiovascular problems, breast mass and cancer and endometrial cancer. This study was performed to evaluate the pre-and post-menopausal pathologies samples of breast. Methods: In this study, 310 pathological samples of breast were studied in pathology center of Shohada hospital in Khorramabad, Iran during 2002 to 2012. The study samples were patients who had underwent mass and tumor biopsy, radical mastectomy and removal of lymph nodes, total and partial mastectomy and their pathologic data had been recorded. Physical examination, patient demographic data and their chief complain were extracted. Data were analyzed by SPSS software (version 16) and Chi-square test. P value less than 0.05 was considered significant. Results: The most common pathological findings in women older than 40 years were respectively fibro adenoma (28.7) and ductal carcinoma (27.3). Fibro adenoma (39.2) was the most common finding in premenopausal stage and ductal carcinoma (34.4) in postmenopausal stage. Conclusion: The most common type of masses in premenopausal period are benign and in postmenopausal are malignant. The regular periodic examination and mammographic follow up are recommended during menopausal age.