(2016) Antimicrobial effect of Ginger (Zingiber officinale) and mallow (Malva sylvestris) hydroalcholic extracts on four pathogen bacteria. Der Pharmacia Lettre. pp. 181-187. ISSN 09755071 (ISSN)
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Abstract
Antibiotic resistance is growing and has limited ability of physicians to treat some infectious diseases. Discovery of new antibiotics or semi-synthetic derivatives affecting on resistant infections are main objectives for treatment of infectious diseases. The aim of this study was to investigate antimicrobial activity of Hydro-alcoholic extracts of ginger (Zingiber officinale) and Mallow (Malva sylvestris) against Pseudomonas aeroginosa, Staphylococcus aureus, Meticillin resistant Staphylococcus aureus and Listeria monocytogenesis as a number of important factors and infectious microorganisms. Antimicrobial effects of Hydro-alcoholic extracts of ginger (Zingiber officinale) and Mallow (Malva sylvestris) was evaluated by micro-plate dilution and disk diffusion methods. MIC of ginger extract for Staphylococcus aureus, Meticillin resistant Staphylococcus aureus, Pseudomonas aeroginosa and Listeria monocytogenesis were 52, 52, 416 1nd 52 μg/ml and MBC of this extract were 104, 104, 416 and 104 μg/ml, respectively. Growth inhibition zone of ginger extract for these bacteria were 16, 9, 7 and 8 mm, respectively. Mallow extract had no antibacterial effects on studied bacteria. Obtained results showed ginger extract can be introduced as bioactive antibiotic in traditional medicine, microbiology and pharmacology sciences.
| Item Type: | Article | ||||||||||||||
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| Keywords: | Antibacterial effect Malva sylvestris extract MBC MIC Zingiber officinale extract antiinfective agent ginger extract plant extract unclassified drug antimicrobial activity Article bacterial strain controlled study disk diffusion drug determination drug effect ginger Listeria monocytogenes Malva Malva sylvestris methicillin resistant Staphylococcus aureus minimum bactericidal concentration minimum inhibitory concentration nonhuman phytochemistry Pseudomonas aeruginosa Staphylococcus aureus | ||||||||||||||
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| Page Range: | pp. 181-187 | ||||||||||||||
| Journal or Publication Title: | Der Pharmacia Lettre | ||||||||||||||
| Journal Index: | Scopus | ||||||||||||||
| Volume: | 8 | ||||||||||||||
| Number: | 1 | ||||||||||||||
| ISSN: | 09755071 (ISSN) | ||||||||||||||
| Depositing User: | مهندس مهدی شریفی | ||||||||||||||
| URI: | http://eprints.medilam.ac.ir/id/eprint/1423 |
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