Abstract

Salmonella are isolated from diarrheal diseases, typhoid fever, bacteriemia and enterocolitis. Salmonella-related diseases are major health problem in most of countries. Scientific research approach has been to achieve plants bioactive substances due to drug resistance and side effects of chemical antimicrobial drugs. Plants can be considered as a source of potentially useful chemicals but only a fraction of them have been used in medicine. We aimed in this review article to present anti Salmonella effects of Iranian native medicinal plants. The information was obtained using key words including Salmonellosis, Salmonella, medicinal plant, essential oil, searching scientific databases scientific information database (SID), Magiran, Google scholar, Blackwell, Wiley, Springer and Sciencedirect. Ten plant families of native medicinal plants of Iran were found to be effective on Salmonella including Thymus multiflora, Thymus vulgaris, Hibiscus sabdariffa, Ferulago angulata, Avicennia marina, Crocus sativus L, Cordia myxa L, Ziziphora clinopodioides, Allium sativum, Teucrium polium L, Satureia hortensis L, Anethum graveolens and Vaccinium arctostaphylosplants. Phenolic compounds, flavonoids and tannins, such as thymol, carvacrol and coumarin have been isolated from the most anti salmonellosis plants. Carvacrol is common antioxidant and bioactive compound in all of these plants. Most used medicinal plants as anti-Salmonella compound has belonged to Lamiaceae family (31 of Iranian native plant families). Active ingredients of Lamiaceae medicinal plants can be produced and entered in pharmaceutical market as anti-Salmonella drugs.