Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Prevalence of Clostridium difficile- associated diarrhea in hospitalized patients with nosocomial diarrhea

Mon May 27 06:22:21 2024

(2005) Prevalence of Clostridium difficile- associated diarrhea in hospitalized patients with nosocomial diarrhea. Iranian Journal of Public Health. pp. 67-72. ISSN 22516085 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Clostridium difficile is a frequently identified cause of nosocomial gastrointestinal disease. It has been proved to be a causative agent in antibiotic-associated, diarrhea, antibiotic-associated colitis, and pseudomembraneous colitis. This study was aimed to determine the prevalence of C.difficile- associated diarrhea in hospitalized patients with nosocomial diarrhea. The 942 hospitalized patients stool samples with nosocomial diarrhea were collected at three hospitals in Tehran from Dec 2002 to Feb 2004.All the stool samples were cultured and in 97 (prevalence: 10.9) samples grew C.difficile that 57 (prevalence: 6.1) isolates were toxigenic by cytotoxicity assay and so 57 patients had C.difficile- associated diarrhea. Results of statistical analysis showed significant difference between the rate of C.difficile associated diarrhea and the patients ages (P<0.05).

Item Type: Article
Creators:
CreatorsEmail
Sadeghifard, N.UNSPECIFIED
Salari, M. H.UNSPECIFIED
Ghassemi, M. R.UNSPECIFIED
Shirazi, M. H.UNSPECIFIED
Feizabadi, M. M.UNSPECIFIED
Kazemi, B.UNSPECIFIED
Majdzadeh, R.UNSPECIFIED
Amin-Harati, F.UNSPECIFIED
Keywords: Antibiotic-associated diarrhea Cytotoxicity assay Iran Nosocomial diarrhea Toxigenic Clostridium difficile aminoglycoside antibiotic agent amoxicillin ampicillin cephalosporin derivative clindamycin penicillin G quinoline derived antiinfective agent tetracycline derivative adolescent adult article bacterium identification bacterium isolation child Clostridium difficile controlled study diarrhea disease association feces analysis female gastrointestinal infection geographic distribution hospital infection hospital patient human infant major clinical study male population distribution prevalence statistical analysis statistical significance
Divisions:
Page Range: pp. 67-72
Journal or Publication Title: Iranian Journal of Public Health
Journal Index: Scopus
Volume: 34
Number: 4
ISSN: 22516085 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/1691

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