Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Rise of antibiotic resistance in clinical enterococcal isolates during 2001-2016 in Iran: a review

Tue May 28 05:00:27 2024

(2018) Rise of antibiotic resistance in clinical enterococcal isolates during 2001-2016 in Iran: a review. New microbes and new infections. pp. 92-99. ISSN 2052-2975 (Print) 2052-2975 (Linking)

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Introduction: The clinical significance of enterococci is mostly related to its antibiotic resistance which contributes to colonization and infection, in particular amongst the hospitalized patients. The present review has examined the literature to provide a comprehensive data on enterococci antibiotic resistance during the last 20 years in Iran. Methods: Search engines such as Google Scholar and PubMed were used to identify all Persian and English-language articles investigating enterococci in Iran from 1996 to 2017. The search terms were "enterococci", "enterococcal", "enterococcus", "Iran", "bacterial resistance", "antibiotic resistance" and "resistance". Results: Decrease in the resistance trend against ampicillin, gentamycin and ciprofloxacin was observed over a period of 15 years (2001 to 2016) in Iran. During a 10 years period from 2001 to 2015, the rate of resistance among Enterococcus faecalis species was less than Enterococcus faecium. The resistancerate, however, was considerably increased for both species during this period. The mean resistance rates for vancomycin, gentamicin, ciprofloxacin, erythromycin, nitrofurantoin, chloramphenicol, trimethoprim-sulfametoxazol, imipenem and teicoplanin were higher among complicated cases (patients with underlying debilitating disorders) compared to general cases (hospitalized or outpatients with no specific underlying disorder). Conclusions: E. faecalis and E. faecium showed a rise in the mean resistance against all the antibiotics during a 10-year period from 2010 to 2015. With the exception of penicillin and ampicillin, resistance to all antibiotics was higher amongst complicated cases compared to general patients.

Item Type: Article
Pourshafie, M. R.UNSPECIFIED
Keywords: Antimicrobial resistance Iran clinical isolates enterococci resistance trend review
Page Range: pp. 92-99
Journal or Publication Title: New microbes and new infections
Journal Index: Pubmed
Volume: 26
Identification Number:
ISSN: 2052-2975 (Print) 2052-2975 (Linking)
Depositing User: مهندس مهدی شریفی

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