Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Molecular Characterization of Methicillin-Resistant Staphylococcus aureus Clones from a Teaching Hospital in Tehran

Wed Sep 28 23:56:50 2022

(2009) Molecular Characterization of Methicillin-Resistant Staphylococcus aureus Clones from a Teaching Hospital in Tehran. Japanese Journal of Infectious Diseases. pp. 309-311. ISSN 1344-6304

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Abstract

A total of 52 methicillin-resistant Staphylococcus aureus (MRSA) clinical isolates were collected from patients attending the teaching hospital of Tehran University of Medical Sciences. Disks containing antibiotics were used to determine the susceptibility of MRSA isolates. Analysis of Sma1 macrorestriction profiles of the 52 MRSA isolates were grouped into three PFGE types. The majority of isolates (n = 49) were clustered into only one major PFGE type, designated as pulsotype A; these belonged to SCCmec type III or IIIA and showed resistance to ampicillin, ciprofloxacin, cotrimoxazole, erythromycin, gentamicin, and tetracycline. The remaining isolates fell into pulsotypes B and C, both belonging to SCCmec-type IV. All MRSA isolates were susceptible to vancomycin, teicoplanin, quinupristin-dalfopristin, linezolid, and tigecycline. The present Study shows that a MRSA clone similar to the Brazilian clone (ST 239) of MRSA, which is a multiresistant MRSA clone with a high level of methicillin resistance, is very common in this teaching hospital in Tehran.

Item Type: Article
Creators:
CreatorsEmail
Fatholahzadeh, B.UNSPECIFIED
Emaneini, M.UNSPECIFIED
Aligholi, M.UNSPECIFIED
Gilbert, G.UNSPECIFIED
Taherikalani, M.UNSPECIFIED
Jonaidi, N.UNSPECIFIED
Eslampour, M. A.UNSPECIFIED
Feizabadi, M. M.UNSPECIFIED
Keywords: spread community strains mrsa chromosome variants Infectious Diseases
Divisions:
Page Range: pp. 309-311
Journal or Publication Title: Japanese Journal of Infectious Diseases
Journal Index: ISI
Volume: 62
Number: 4
ISSN: 1344-6304
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/887

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