Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Survey of both hepatitis B virus (HBsAg) and hepatitis C virus (HCV-Ab) coinfection among HIV positive patients

Wed May 22 12:33:33 2024

(2009) Survey of both hepatitis B virus (HBsAg) and hepatitis C virus (HCV-Ab) coinfection among HIV positive patients. Virology Journal. p. 5. ISSN 1743-422X

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Background: HIV, HBVand HCV is major public health concerns. Because of shared routes of transmission, HIV-HCV coinfection and HIV-HBV coinfection are common. HIV-positive individuals are at risk of coinfection with HBV and HCV infections. The prevalence rates of coinfection with HBV and HCV in HIV-patients have been variable worldwide depending on the geographic regions, and the type of exposure. Aim: This study aimed to examine HBV and HCV coinfection serologically and determine the shared and significant factors in the coinfection of HIV-positive patients. Methods: This descriptive, cross-sectional study was carried out on 391 HIV-positive patients including 358 males and 33 females in Lorestan province, west Iran, to survey coinfection with HBsAg and anti-HCV. The retrospective demographic data of the subjects was collected and the patients' serums were analyzed by ELISA kits including HBsAg and anti-HCV. The collected data was analyzed with SPSS software (15) and Chi-square. Fisher's exact test with 5 error intervals was used to measure the correlation of variables and infection rates. Results: The results of the study indicated that the prevalence of coinfection in HIV-positive patients with hepatitis viruses was 94.4 (370 in 391), out of whom 57 (14.5) cases were HBsAg positive, 282 (72) cases were anti-HCV positive, and 31 (7.9) cases were both HBsAg and anti-HCV positive. Conclusion: There was a significant correlation between coinfection with HCV and HBV and/or both among HIV-positive patients depending on different variables including sex, age, occupation, marital status, exposure to risk factors.(p < 0.001).

Item Type: Article
Ebrahimzade, F.UNSPECIFIED
Keywords: human-immunodeficiency-virus infected patients northern india prevalence cohort Virology
Page Range: p. 5
Journal or Publication Title: Virology Journal
Journal Index: ISI
Volume: 6
Identification Number:
ISSN: 1743-422X
Depositing User: مهندس مهدی شریفی

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