Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

CERUMEN AS A POTENTIAL RISK FOR TRANSMISSION OF HEPATITIS B VIRUS

Mon Oct 3 01:02:54 2022

(2011) CERUMEN AS A POTENTIAL RISK FOR TRANSMISSION OF HEPATITIS B VIRUS. Acta Microbiologica Et Immunologica Hungarica. pp. 105-112. ISSN 1217-8950

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Abstract

Hepatitis B virus (HBV) transmission via blood and other body fluids from infected individuals to healthy people has been largely demonstrated. However, in the current literature, there is little information available on the potential role of cerumen in HBV transmission. Cerumen and blood were collected from 70 patients infected with HBV and 70 volunteer healthy people were selected as the control group, and the samples were evaluated by ELISA and Real-time PCR. All the patients proved positive for HBsAg and anti HBc total. Sixty-one of the 70 cerumen samples of cases (82.1) and 5 (7) of controls were positive for HBV DNA with ranges from 1.53 x 10(2) to 2.9 x 10(8) and 1.3 x 10(2) - 2.6 x 10(5)/ml, respectively. In three patients, the level of HBV DNA in cerumen was higher than that in the serums. The patients who were positive for HBeAg showed a higher rate of HBV DNA in the serum and cerumen. The results of this study showed the level of HBV DNA as a probably indicator of high risk transmission factor, which was present in the cerumen of chronic hepatitis B patients in west of Iran.

Item Type: Article
Creators:
CreatorsEmail
Gholami-Parizad, E.UNSPECIFIED
Taherikalani, M.UNSPECIFIED
Mozaffar-Sabet, N. A.UNSPECIFIED
Asmar, M.UNSPECIFIED
Gholami-Parizad, S.UNSPECIFIED
Khosravi, A.UNSPECIFIED
Emaneini, M.UNSPECIFIED
Asadollahi, P.UNSPECIFIED
Keywords: Hepatitis B virus chronic hepatitis real-time PCR cerumen DNA blood iran Immunology Microbiology
Divisions:
Page Range: pp. 105-112
Journal or Publication Title: Acta Microbiologica Et Immunologica Hungarica
Journal Index: ISI
Volume: 58
Number: 2
Identification Number: https://doi.org/10.1556/AMicr.58.2011.2.3
ISSN: 1217-8950
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/844

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