Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

PREVALENCE OF GENOMIC ISLAND PAPI-1 IN CLINICAL ISOLATES OF PSEUDOMONAS AERUGINOSA IN IRAN

(2012) PREVALENCE OF GENOMIC ISLAND PAPI-1 IN CLINICAL ISOLATES OF PSEUDOMONAS AERUGINOSA IN IRAN. Southeast Asian Journal of Tropical Medicine and Public Health. pp. 431-435. ISSN 0125-1562

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Abstract

Pseudomonas aeruginosa, a gram-negative rod-shaped bacterium, is an opportunistic pathogen, which causes various serious diseases in humans and animals. The aims of this study were to evaluate of the presence of genomic island PAPI-1 in Pseudomonas aeruginosa isolated from Reference Laboratory of Ilam, Milad Hospital and Emam Khomeini Hospital, Iran and to study the frequency of extended spectrum beta-lactamases (ESBLs) among isolates. Forty-eight clinical isolates of P. aeruginosa were obtained during April to September 2010, and were evaluated for ESBLs by screening and confirmatory disk diffusion methods and PAPI-1 by PCR. Fifteen of 48 P. aeruginosa isolates were positive for ESBLs and 17 isolates positive for PAPI-1. This was first study of the prevalence of PAPI-1 in clinical isolates of P. aeruginosa in Iran, showing that most of PAPI-1 positive strains had high levels of antibiotic resistance and produced ESBLs.

Item Type: Article
Keywords: P. aeruginosa PAPI-1 ESBLs pathogenicity islands evolution resistance genes Public, Environmental & Occupational Health Infectious Diseases Tropical Medicine
Page Range: pp. 431-435
Journal or Publication Title: Southeast Asian Journal of Tropical Medicine and Public Health
Journal Index: ISI
Volume: 43
Number: 2
ISSN: 0125-1562
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/798

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