Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Prevalence of Human Immunodeficiency Virus in Iranian Blood Donors: A Systematic Review and Meta-Analysis

Thu Oct 6 07:48:34 2022

(2018) Prevalence of Human Immunodeficiency Virus in Iranian Blood Donors: A Systematic Review and Meta-Analysis. Archives of Iranian Medicine. pp. 260-267. ISSN 1029-2977

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Abstract

Background: The probability of HIV transmission through contaminated blood and blood products is eye catching. 5-10 of blood products are contaminated with HIV. Therefore, it is essential to provide safe blood supply to prevent transmission of infectious diseases. Current systematic review and meta-analysis was conducted to evaluate the weighted prevalence of HIV in Iranian blood donors. Methods: This study was reported according to PRISMA checklist for systematic reviews and meta-analysis. Required data were collected by using key words such as "HIV", "blood donation" OR "blood donors", "epidemiology" OR "prevalence", "blood transfusion" and "Iran", in international databases including PubMed, Scopus, Web of Science, Cochrane, Embase and national databases including Magiran, IranMedex and Scientific Information Databank. Papers were searched until December 2017. Cochran's Q test and I-2 index were used to assess the heterogeneity among studies. Results: A total of 49 studies including 5 403 170 donors entered this meta-analysis. According to analysis, the prevalence of HIV-positive patients among Iran blood donors was estimated 7.9/100 000 (95 CI: 0.000052-0.000121). The highest prevalence was related to the central region of Iran (11.3/100,000 95% CI: 0.000063-0.0002%) and Kermanshah province (49.2/100 000 95% CI: 0.000273-0.000888%) and the lowest prevalence was related to the eastern region (1/100 000 95% CI: 0.0000010.000072%) and Khorasan Razavi province (0.9/100 000 95% CI: 0.000001-0.000139%. Conclusion: The overall HIV prevalence in Iranian blood donors is low and satisfying. However, the high prevalence in some regions and provinces should be reviewed more meticulously.

Item Type: Article
Creators:
CreatorsEmail
Musavi, H.UNSPECIFIED
Rahimi, H.UNSPECIFIED
Kooti, W.UNSPECIFIED
Dorostkar, R.UNSPECIFIED
Azami, M.UNSPECIFIED
Sharghi, M.UNSPECIFIED
Ashrafi-Zadeh, H.UNSPECIFIED
Firoozbakht, M.UNSPECIFIED
Taheri, R. A.UNSPECIFIED
Keywords: Blood donors Human immunodeficiency Meta-analysis Prevalence Virus transmissible viral-infections hepatitis-c virus hiv-infection syphilis infections risk-factors b-virus trends epidemiology hcv donations General & Internal Medicine
Divisions:
Page Range: pp. 260-267
Journal or Publication Title: Archives of Iranian Medicine
Journal Index: ISI
Volume: 21
Number: 6
ISSN: 1029-2977
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/74

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