Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Risk factors for acquisition of ventilator-associated pneumonia in adult intensive care units

Sun Aug 14 02:24:32 2022

(2013) Risk factors for acquisition of ventilator-associated pneumonia in adult intensive care units. Pakistan Journal of Medical Sciences. pp. 1105-1107. ISSN 1682-024X

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Abstract

Objective: Ventilator Associated Pneumonia (VAP) has an imperative place amongst nosocomial infections leading to increase morbidity and mortality rates. The present study aimed to determine risk factors for acquisition of ventilator-associated pneumonia in an intensive care unit (ICU). Methods: A nested case-control study was carried out from September 2007 to June 2008. All 183 patients hospitalized at the adult ICU ward in Be'sat Hospital, Sanandaj city western Iran over a 48 hour period were included. Bacteriologic diagnosis and antibiotic susceptibility patterns were performed based on Edward & Ewing's methods and CLSI system guidelines. Results: Of the 149 samples which were taken from endotracheal tubes of 183 patients, 48 cases were diagnosed for VAP with an incidence rate of 26.2. Mean duration of hospitalization was 23.4 +/- 10.2 days. The maximum and minimum antibiotic resistance for the gram negative bacteria was 93.3 for Cefalotin and 50 for Amikacin. The main risk factors for acquisition of ventilator-associated pneumonia were mechanical ventilation (Adjusted OR: 1.55, 95 CI: 1.37-1.74), history of antibiotic consumption (AOR: 8.92, CI: 1.16-66.66) and fever (AOR: 3.11, CI: 1.22-7.93). Conclusions: VAP is significantly related to ICU hospitalization, mechanical ventilation and history of antibiotics consumption. Cefalotin and Amikacin showed the highest and lowest antibiotic resistance against gram negative bacteria respectively.

Item Type: Article
Creators:
CreatorsEmail
Lahoorpour, F.UNSPECIFIED
Delpisheh, A.UNSPECIFIED
Afkhamzadeh, A.UNSPECIFIED
Keywords: Ventilator-Associated Pneumonia (VAP) Intensive Care Unit impact epidemiology resistant evolution outcomes icu General & Internal Medicine
Divisions:
Page Range: pp. 1105-1107
Journal or Publication Title: Pakistan Journal of Medical Sciences
Journal Index: ISI
Volume: 29
Number: 5
ISSN: 1682-024X
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/710

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