Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Seroepidemiological Survey of Human Visceral Leishmaniasis in Ilam Province, West of Iran In 2013

Thu May 23 04:09:46 2024

(2015) Seroepidemiological Survey of Human Visceral Leishmaniasis in Ilam Province, West of Iran In 2013. Iranian Journal of Parasitology. pp. 56-61. ISSN 1735-7020

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Background: Visceral leishmaniasis (VL) as one of the most important human parasitic disease is endemic in some parts of Iran. Several cases of VL have been reported recently in the Ilam Province. The current study aimed to assess the present status of human VL in the region. Methods: A random cluster sampling method was used to collect 456 serums samples from the children up to 12 years of age and 10 of adults living in urban and rural areas of the province. All the collected serum samples were tested by direct agglutination test (DAT) to detect anti-Leishmania infantum antibodies. Results: Of the examined 456 serum samples with direct agglutination test (DAT), only 21 (0.43) sera showed anti-Leishmania antibodies at titers 1:400 and higher. Distribution of anti-Leishmania antibodies titers were: 1:400(n=4), 1:800(n=11), 1:1600(n=3), 1:3200(n=1), and 1:6400(n=1). Individuals with titers >= 1:3200 showed clinical signs and symptoms such as fever and splenomegaly. The highest and lowest seropositivity were observed in the age groups of 5-9 and >15 years old, respectively. There were no significant difference between the rate of seropositivity in males and females. Conclusion: VL with a low prevalence circulates in some parts of Ilam province, particularly in the southern parts. Complementary studies should be needed to find animal reservoir hosts and vectors. Furthermore, health systems and physicians should pay particular attention to the disease.

Item Type: Article
Keywords: Visceral leishmaniasis Human Seroprevalence Iran Parasitology
Page Range: pp. 56-61
Journal or Publication Title: Iranian Journal of Parasitology
Journal Index: ISI
Volume: 10
Number: 1
ISSN: 1735-7020
Depositing User: مهندس مهدی شریفی

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