Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

The rationale behind antibiotic resistance pattern in Klebsiella pneumoniae

Wed Sep 28 13:32:53 2022

(2016) The rationale behind antibiotic resistance pattern in Klebsiella pneumoniae. Tropical Biomedicine. pp. 383-386. ISSN 0127-5720

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Abstract

Presently, there is an increase in antibiotic resistance in bacteria, due to relax prescription of antibiotics, especially in Iran. Undoubtedly, in toxin antitoxin (TA) system, a toxin neutralized by antitoxin, which known as a potent antimicrobial target; but there is no extensive survey on the prevalence of TA loci in large scale of Klebsiella pneumoniae. Therefore, this study aims to determine the prevalence of different TA loci in clinical and environmental K. pneumoniae isolates. For this reason, 48 K. pneumoniae clinical isolates and 49 K. pneumoniae environmental isolates were subjected for evaluation of different TA loci. The results of current study indicated that there is no association between antibiotic resistances and presence of TA loci in clinical and environmental K. pneumoniae. The role of TA loci as a potent target in antibiotic resistant K. pneumoniae has been complicated. Therefore, more studies should be performed to explain why TA loci are presented in K. pneumoniae and what is the rationale behind antibiotic resistant K. pneumoniae?

Item Type: Article
Creators:
CreatorsEmail
Valian, F.UNSPECIFIED
Sadeghifard, N.UNSPECIFIED
Pakzad, I.UNSPECIFIED
Valizadeh, N.UNSPECIFIED
Karami, S.UNSPECIFIED
Badakhsh, B.UNSPECIFIED
Sekawi, Z.UNSPECIFIED
Taherikalani, M.UNSPECIFIED
Valadbeigi, H.UNSPECIFIED
Ghafourian, S.UNSPECIFIED
Keywords: escherichia-coli cell-death bacteria system toxin Parasitology Tropical Medicine
Divisions:
Page Range: pp. 383-386
Journal or Publication Title: Tropical Biomedicine
Journal Index: ISI
Volume: 33
Number: 2
ISSN: 0127-5720
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/463

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