Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Determination of Risk Factors Affecting Survival of Patients with Gastric Adenocarcinoma in Hamadan, Iran

Sun Jun 26 21:05:18 2022

(2016) Determination of Risk Factors Affecting Survival of Patients with Gastric Adenocarcinoma in Hamadan, Iran. Middle East Journal of Cancer. pp. 125-129. ISSN 2008-6709

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Abstract

Background: Gastric cancer is the second leading cause of cancer death. The aim of this study was to determine the survival rate affected by risk factors in patients with gastric adenocarcinoma. Methods: We performed this retrospective cohort study on patients diagnosed with gastric adenocarcinoma during 2005-2012 in Hamadan, Iran. All patients with pathological diagnosis enrolled in the study. The effects of patients' demographical and pathological data were assessed in terms of survival. The univariate and multivariate Weibull models were used to determine the effects of these factors on survival rate. Data was analyzed by SPSS16 and STATA10 software. Results: A total of 112 gastric adenocarcinoma patients were followed. Patients included 74 ( 66.1) males. During the follow-up, 102 ( 91.1) patients died. Patients' had a mean ( SD) survival of 21.9 ( 1.9) months and a median survival of 15 months. The "one-, three-and five-year survival rates were 62, 16 and 9 respectively. The results showed that metastasis, chemotherapy, tumor site and grade had statistically significant impacts on patient survival. Conclusion: A potentially important role for tumor grade, tumor site, metastasis, and pathologic stage of disease existed in terms of patient survival after surgery. The current research has indicated that neoadjuvant treatment increased survival in patients with gastric adenocarcinoma. It is expected that the prognostic model based on the mentioned factors may assist individual risk stratification and help in the planning of potential forthcoming studies.

Item Type: Article
Creators:
CreatorsEmail
Roshanaei, G.UNSPECIFIED
Rostampour, F.UNSPECIFIED
Javadi, M.UNSPECIFIED
Behnoud, S.UNSPECIFIED
Ghannad, M. S.UNSPECIFIED
Keywords: Gastric adenocarcinoma Survival Adjuvants Pharmaceutics Therapeutics cancer patients surgery Oncology
Divisions:
Page Range: pp. 125-129
Journal or Publication Title: Middle East Journal of Cancer
Journal Index: ISI
Volume: 7
Number: 3
ISSN: 2008-6709
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/454

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