Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

A Comparative Study on the Effect of Intrathecal Bupivacaine vs. Ropivacaine on Maternal and Neonatal Outcomes After Cesarean Section: A Systematic Review and Meta-analysis

Thu Feb 22 17:34:08 2024

(2023) A Comparative Study on the Effect of Intrathecal Bupivacaine vs. Ropivacaine on Maternal and Neonatal Outcomes After Cesarean Section: A Systematic Review and Meta-analysis. Anesthesiology and Pain Medicine. ISSN 22287523 (ISSN)

Full text not available from this repository.

Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Context: The type of anesthesia in cesarean section can affect the mother and baby. This study aimed to determine the comparative effect of intrathecal hyperbaric bupivacaine vs. hyperbaric ropivacaine on maternal and neonatal outcomes after cesarean section. Evidence Acquisition: PubMed, Web of Science, Embase, Google Scholar, IranDoc, MagIran, and Scopus databases were searched from 1 September 2022 to 1 November 2022. Eighteen clinical trials with 1542 patients were included in the analysis. Results: There was no statistically significant difference in hypotension, bradycardia, and Apgar score between the 2 groups (P > 0.05). The risk of nausea (relative risk (RR), 1.526; 95 CI, 1.175-1.981; P = 0.001) and vomiting (RR, 1.542; 95 CI, 1.048-2.268; P = 0.02) caused by bupivacaine was 0.53 and 0.54 higher than that of ropivacaine. The incidence of shivering (RR, 2.24; 95 CI, 1.480-3.39; P = 0.00) was 2.24 times higher in the bupivacaine group than in the ropivacaine group. The average onset time of sensory block (standardized mean difference (SMD),-0.550; 95 CI,-1.054 to-0.045; P = 0.032) and motor block (SMD,-0.812; 95 CI,-1.254 to-0.371; P = 0.000) was significantly lower in the bupivacaine group than in the ropivacaine group. Conclusions: Despite the fact that ropivacaine and bupivacaine are effective in cesarean section, ropivacaine is more favorable because of less hemodynamic changes, less duration of sensory and motor block, and fewer side effects, which are effective in patient recovery. © 2023, Author(s).

Item Type: Article
Creators:
CreatorsEmail
Jaafarpour, M.UNSPECIFIED
Vasigh, A.UNSPECIFIED
Najafi, F.UNSPECIFIED
Sayadi, H.UNSPECIFIED
Shafiei, E.UNSPECIFIED
Keywords: Bupivacaine Cesarean Section Mothers Ropivacaine Spinal Anesthesia Apgar score bradycardia clinical trial (topic) comparative study drug effect drug therapy hemodynamics human hyperbaric pressure hypotension intrathecal drug administration meta analysis mother nausea and vomiting newborn assessment outcome assessment Preferred Reporting Items for Systematic Reviews and Meta-Analyses Review risk factor shivering systematic review
Divisions:
Journal or Publication Title: Anesthesiology and Pain Medicine
Journal Index: Scopus
Volume: 13
Number: 3
Identification Number: https://doi.org/10.5812/aapm-134732
ISSN: 22287523 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/4527

Actions (login required)

View Item View Item