Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Clinical Efficacy of Probiotics on Oral Health: A Systematic Review of Clinical Trials

Sat Apr 20 01:14:13 2024

(2023) Clinical Efficacy of Probiotics on Oral Health: A Systematic Review of Clinical Trials. Current Pharmaceutical Biotechnology. pp. 1916-1927. ISSN 1389-2010

Full text not available from this repository.

Official URL: http://apps.webofknowledge.com/InboundService.do?F...

Abstract

Introduction Periodontal diseases and dental caries are the two most common dental diseases caused by the dental plaque. Objective The aim of the present study was to review the clinical efficacy of probiotics for oral health in randomized controlled trials. Methods An electronic search was conducted in December 2021 in Embase Medline The Cochrane Library ProQuest and Google Scholar using the following keywords: "mouthwash" and "probiotics". The titles and abstracts of 3,775 articles were screened and 24 publications that fulfilled the inclusion criteria were included. Results A total of 24 clinical trials were reviewed, including 1612 participants receiving either probiotics or mouth treatments. The results of this review indicated that individuals receiving probiotic products have a significant reduction (65 reduction p < 0.05) in the count of Streptococcus mutants in their mouths. It was also found that probiotic products were more effective or equal in effect compared to chlorhexidine in reducing oral pathogens, gingival index, and plaque index scores. On the other hand, the consumption of xylitol mouthwash was shown to cause an improvement in salivary parameters. Considering their safety and effectiveness, the use of probiotic products, such as kefir and mouthwashes, has been recommended against cariogenic bacteria and periodontal diseases. Conclusion Probiotics are considered a safe alternative to conventional therapies such as chlorhexidine and fluoride. Co-administration of chlorhexidine fluoride and probiotics seems to be a perfect package

Item Type: Article
Creators:
CreatorsEmail
Navidifar, T.UNSPECIFIED
Ari, M. M.UNSPECIFIED
Alipourkermani, A.UNSPECIFIED
Afifirad, R.UNSPECIFIED
Asadollahi, P.UNSPECIFIED
Veisi, A.UNSPECIFIED
Ghanavati, R.UNSPECIFIED
Darbandi, A.UNSPECIFIED
Keywords: Probiotics Streptococcus mutans oral health mouthwash clinical trials diseases full-mouth disinfection streptococcus-mutans chlorhexidine pretreatment double-blind consumption regrowth children plaque Biochemistry & Molecular Biology Pharmacology & Pharmacy
Divisions:
Page Range: pp. 1916-1927
Journal or Publication Title: Current Pharmaceutical Biotechnology
Journal Index: ISI
Volume: 24
Number: 15
Identification Number: https://doi.org/10.2174/1389201024666230405135457
ISSN: 1389-2010
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/4456

Actions (login required)

View Item View Item