(2023) Long non-coding RNAs and gastric cancer: An update of potential biomarkers and therapeutic applications. Biomedicine & Pharmacotherapy. p. 24. ISSN 0753-3322
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Abstract
The frequent metastasis of gastric cancer (GC) complicates the cure and therefore the development of effective diagnostic and therapeutic approaches is urgently necessary. In recent years, lncRNA has emerged as a drug target in the treatment of GC, particularly in the areas of cancer immunity, cancer metabolism, and cancer metastasis. This has led to the demonstration of the importance of these RNAs as prognostic, diagnostic and therapeutic agents. In this review, we provide an overview of the biological activities of lncRNAs in GC devel-opment and update the latest pathological activities, prognostic and diagnostic strategies, and therapeutic op-tions for GC-related lncRNAs.
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| Keywords: | Long non-coding RNA Gastric cancer Molecular mechanisms Diagnostic Cancer treatment Clinical relevance epithelial-mesenchymal-transition promotes cisplatin resistance exosome-mediated transfer cell-proliferation inhibits apoptosis noninvasive biomarker helicobacter-pylori lncrna snhg5 invasion malat1 Research & Experimental Medicine Pharmacology & Pharmacy | ||||||||||||||||||||
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| Page Range: | p. 24 | ||||||||||||||||||||
| Journal or Publication Title: | Biomedicine & Pharmacotherapy | ||||||||||||||||||||
| Journal Index: | ISI | ||||||||||||||||||||
| Volume: | 163 | ||||||||||||||||||||
| Identification Number: | https://doi.org/10.1016/j.biopha.2023.114407 | ||||||||||||||||||||
| ISSN: | 0753-3322 | ||||||||||||||||||||
| Depositing User: | مهندس مهدی شریفی | ||||||||||||||||||||
| URI: | http://eprints.medilam.ac.ir/id/eprint/4398 |
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