Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Diagnosis and Treatment of Coagulopathy Caused by the New Coronavirus: A Systematic Review and Meta-Analysis Protocol

Wed Jul 17 17:51:24 2024

(2023) Diagnosis and Treatment of Coagulopathy Caused by the New Coronavirus: A Systematic Review and Meta-Analysis Protocol. Advanced Biomedical Research. p. 5. ISSN 2277-9175

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Background: The new coronavirus is an agent of respiratory infections associated with thrombosis in vital organs. This study aimed to propose a better diagnosis and treatment of coagulation disorders caused by the new coronavirus (Covid-19). Materials and Methods: Search in Cochrane central, Web of Science, PubMed, Scopus, and Ovid will be done. Also, according to the inclusion criteria, cross-sectional studies, cohort, clinical trial, and case-control will be included without gender and language restriction. Participants will also be Covid-19 patients with coagulation disorders. Any disagreement in the stages of screening, selection, and extraction of data between the two reviewers will be resolved by discussion, then if not resolved, the opinion of expert reviewers will be used. The risk of bias will be assessed using the NOS (Newcastle-Ottawa scale) tool for cross-sectional study, cohort and case-control, and the Cochrane checklist for clinical trials study. Metaanalysis of included studies that are similar based on the methodology will be done. Also, a fixed or random-effect model will be used for this it. Heterogeneity indices (I2), odds ratio (OR), risk ratio (RR), mean difference, and 95 confidence interval will also be calculated by Stata V.13.0 (Corporation, College Station TX). Results: Treatment with anticoagulants will reduce the severity of thrombosis and lung disease in patients. D-dimer measurement will also be a diagnosis indicator of thrombosis. Conclusions: Simultaneous study of coagulation disorders and thrombosis in patients and development of a Godliness based on it will play a treatment role in the follow-up of the coronavirus disease.

Item Type: Article
Shanbehzadeh, M.UNSPECIFIED
Kazemi-Arpanahi, H.UNSPECIFIED
Keywords: Coronavirus diagnosis treatment thrombosis covid-19 Research & Experimental Medicine
Page Range: p. 5
Journal or Publication Title: Advanced Biomedical Research
Journal Index: ISI
Volume: 12
Number: 1
Identification Number:₄₀₃₂₁
ISSN: 2277-9175
Depositing User: مهندس مهدی شریفی

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