Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Predicting Epithelial Ovarian Cancer First Recurrence with Random Survival Forest: Comparison Parametric, Semi-Parametric, and Random Survival Forest Methods

Tue Jun 25 03:22:24 2024

(2020) Predicting Epithelial Ovarian Cancer First Recurrence with Random Survival Forest: Comparison Parametric, Semi-Parametric, and Random Survival Forest Methods. Journal of Biostatistics and Epidemiology. pp. 267-274. ISSN 23834196 (ISSN)

Full text not available from this repository.

Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Objective: Rapid technological advances in the last century and the large amount of information have made it difficult to analyze a large number of independent variables. In such circumstances, the existence of interactions of different degrees in the model is expected, in this case, the Cox model cannot be useful and the nonparametric method of random survival forest can be a useful alternative. This study compares the prediction error of random survival forest with Cox and Weibull models in predicting the time to the first recurrence in patients with epithelial ovarian cancer. Method: In this retrospective study, the records of patients with epithelial ovarian cancer who referred to Imam Hossein Hospital in Tehran from 2007 to 2018 were used. To investigate the factors affecting the first recurrence of these patients, RSF was fitted to the data. Finally, prediction error of Cox, Weibull and RSF were compared using C-Index and Brier score. Results: Brier score was calculated 0.16 for RSF, and 0.24 for Cox, also C-Index was calculated 0.34 for RSF and 0.42 for Cox. Brier score was calculated 0.092 for Cox and 0.089 for Weibull, so the prediction error of RSF was lower than both Cox and Weibull models. Conclusion: Random survival forest with a suitable fit on many variables and without the need for a special default with a prediction error less than the Weibull and Cox methods can predict the response variable when confronted with high-dimensional data. © 2020 Tehran University of Medical Sciences.

Item Type: Article
Creators:
CreatorsEmail
Deldar, M.UNSPECIFIED
Anbiaee, R.UNSPECIFIED
Sayehmiri, K.UNSPECIFIED
Keywords: Cox Epithelial ovarian cancer First recurrent Random survival Weibull
Divisions:
Page Range: pp. 267-274
Journal or Publication Title: Journal of Biostatistics and Epidemiology
Journal Index: Scopus
Volume: 6
Number: 4
Identification Number: https://doi.org/10.18502/jbe.v6i4.5680
ISSN: 23834196 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/4320

Actions (login required)

View Item View Item