Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

An overview on inactivated and live-attenuated SARS-CoV-2 vaccines

Thu Feb 2 18:50:20 2023

(2022) An overview on inactivated and live-attenuated SARS-CoV-2 vaccines. Journal of Clinical Laboratory Analysis. p. 12. ISSN 0887-8013

Full text not available from this repository.

Official URL: http://apps.webofknowledge.com/InboundService.do?F...

Abstract

After about 2 years since severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first infections were detected in Wuhan city of China in December 2019, which was followed by a worldwide pandemic with a record of 5.41 million deaths. Due to urgent need for the development of a safe and effective vaccine for coronavirus disease 2019 (COVID-19), attempts for producing efficient vaccines are inexhaustibly continuing. According to a report by the World Health Organization (WHO) on COVID-19 vaccine tracker and landscape, there are 149 vaccine candidates all over the world. Inactivated SARS-CoV-2 vaccines as a conventional vaccine platform consist of whole virus particles grown in cell culture and inactivated by chemicals. Because of benefits such as antigenic similarity to real virion inducing humoral and cellular immune responses and ease for transport and storage, these vaccines, including the vaccines produced by Bharat Biotech, Sinopharm, and Sinovac, are in use at large scales. In this study, we have a review on inactivated SARS-CoV-2 vaccines that are passing their phase 3 and 4 clinical trials, population which was included in the trials, vaccine producers, the efficiency, adverse effects, and components of vaccines, and other vaccine features.

Item Type: Article
Creators:
CreatorsEmail
Khoshnood, S.UNSPECIFIED
Arshadi, M.UNSPECIFIED
Akrami, S.UNSPECIFIED
Koupaei, M.UNSPECIFIED
Ghahramanpour, H.UNSPECIFIED
Shariati, A.UNSPECIFIED
Sadeghifard, N.UNSPECIFIED
Heidary, M.UNSPECIFIED
Keywords: attenuated vaccine COVID-19 inactivated vaccine review SARS-CoV-2 immunogenicity safety variants Medical Laboratory Technology
Divisions:
Page Range: p. 12
Journal or Publication Title: Journal of Clinical Laboratory Analysis
Journal Index: ISI
Volume: 36
Number: 5
Identification Number: https://doi.org/10.1002/jcla.24418
ISSN: 0887-8013
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/4040

Actions (login required)

View Item View Item