Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Ex Vivo Evaluation of Thymus daenensis as an Antioxidant and Antibacterial Medicinal Herb

Wed Nov 30 07:54:23 2022

(2016) Ex Vivo Evaluation of Thymus daenensis as an Antioxidant and Antibacterial Medicinal Herb. Drug Research. pp. 657-659. ISSN 2194-9379

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Abstract

Herbal medicines are defined as traditionally used natural products. The current study in an attempt try to investigate the antibacterial activity on extended spectrum beta-lactamases (ESBL), methalo beta-lactamases (MBL) producing gram negative bacteria and methicillin resistant Staphylococcus aureus (MRSA) and subsequently, to determine the antioxidant activity of Thymus daenensis. For this reasons, firstly cytotoxicity of T. daenensis was determined by MTT assay. Then, essential oil was subjected for antibacterial and antioxidant activity. Our results demonstrated that 15mg/ml concentration of T. daenensis inhibited both P. aeruginosa producing MBL and E.coli producing ESBL, while this value was 25mg/ml concentration for MRSA inhibition. The association between phenolic compound and antioxidant activity was found for the ABTS(center dot+) method (43.52) in the lowest level, while, for FRAD and DPPH center dot methods the opposite story occurred (70.5 correlation for DPPH center dot and 50.9 for FRAD). Our findings suggested that T. daenensis has a potential herbal medicine that should be considered as an antibacterial and antioxidant with very low toxicity.

Item Type: Article
Creators:
CreatorsEmail
Saidi, M.UNSPECIFIED
Sadeghifard, N.UNSPECIFIED
Kazemian, H.UNSPECIFIED
Sekawi, Z.UNSPECIFIED
Badakhsh, B.UNSPECIFIED
Friadian, S.UNSPECIFIED
Ghafourian, S.UNSPECIFIED
Keywords: antioxidant antibacterial thymus daenensis commonly consumed vegetables essential oils oxidation assay Pharmacology & Pharmacy Chemistry
Divisions:
Page Range: pp. 657-659
Journal or Publication Title: Drug Research
Journal Index: ISI
Volume: 66
Number: 12
Identification Number: https://doi.org/10.1055/s-0042-113457
ISSN: 2194-9379
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/404

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