Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Design and Development of an Intelligent System for Predicting 5-Year Survival in Gastric Cancer

Thu Feb 2 18:08:32 2023

(2022) Design and Development of an Intelligent System for Predicting 5-Year Survival in Gastric Cancer. Clinical Medicine Insights-Oncology. p. 13.

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Abstract

BACKGROUND: Gastric cancer remains one of the leading causes of worldwide cancer-specific deaths. Accurately predicting the survival likelihood of gastric cancer patients can inform caregivers to boost patient prognostication and choose the best possible treatment path. This study intends to develop an intelligent system based on machine learning (ML) algorithms for predicting the 5-year survival status in gastric cancer patients. METHODS: A data set that includes the records of 974 gastric cancer patients retrospectively was used. First, the most important predictors were recognized using the Boruta feature selection algorithm. Five classifiers. including J48 decision tree (DT), support vector machine (SVM) with radial basic function (RBF) kernel, bootstrap aggregating (Bagging), hist gradient boosting (HGB). and adaptive boosting (AdaBoost). were trained for predicting gastric cancer survival. The performance of the used techniques was evaluated with specificity. sensitivity, likelihood ratio, and total accuracy. Finally, the system was developed according to the best model. RESULTS: The stage, position, and size of tumor were selected as the 3 top predictors for gastric cancer survival. Among the 6 selected ML algorithms, the HGB classifier with the mean accuracy. mean specificity, mean sensitivity. mean area under the curve. and mean F1-score of 88.37. 86.24, 89.72. 88.11, and 89.91. respectively. gained the best performance. CONCLUSIONS: The ML models can accurately predict the 5-year survival and potentially act as a customized recommender for decision-making in gastric cancer patients. The developed system in our study can improve the quality of treatment, patient safety, and survival rates; it may guide prescribing more personalized medicine.

Item Type: Article
Creators:
CreatorsEmail
Afrash, M. R.UNSPECIFIED
Shanbehzadeh, M.UNSPECIFIED
Kazemi-Arpanahi, H.UNSPECIFIED
Keywords: Machine learning data mining survival stomach neoplasm artificial-intelligence prognosis model Oncology
Divisions:
Page Range: p. 13
Journal or Publication Title: Clinical Medicine Insights-Oncology
Journal Index: ISI
Volume: 16
Identification Number: https://doi.org/10.1177/11795549221116833
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/4019

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