Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

The effect of Atorvastatin on chronic subdural hematoma status: A systematic review of drug therapy

Wed Jul 24 10:49:45 2024

(2022) The effect of Atorvastatin on chronic subdural hematoma status: A systematic review of drug therapy. Eurasian Chemical Communications. pp. 1130-1137. ISSN 2717-0535

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Abstract

Atorvastatin (ATO) with its chemical formula of (C33H35FN2O5) is one of the cholesterol-lowering drugs that can also reduce hematoma volume (HV). Considering the importance of pharmacological treatments in improving the patient condition, the aim of this study was to evaluate the ATO effect on chronic subdural hematoma (CSDH) status. In this systematic review (SR) study, all articles about the ATO effect on CSDH status were entered into a study, without time constraints, by two authors who were professional in SR articles. In the initial search, 176 articles were found, of which 73 articles were deleted due to duplicate records, and after further review and removal of unrelated articles, this number reduced to 11 articles, and systematic review data was reported with 11 articles. In all articles, radiological clinical findings were used to diagnose hematoma. In most of the reviewed articles, atorvastatin was effective in reducing subdural hemorrhage. The articles ranged from 2014 to 2021, the total sample size was 1278 patients and the follow-up period varied from 2 months to 4 years. Concerning the ATO effect in reducing HV status in CSDH patients, it is recommended to prescribe this drug to improve HV levels.

Item Type: Article
Creators:
CreatorsEmail
Hatefi, M.UNSPECIFIED
Komlakh, K.UNSPECIFIED
Keywords: Atorvastatin chronic subdural hematoma systematic review biomarkers risk Chemistry
Divisions:
Page Range: pp. 1130-1137
Journal or Publication Title: Eurasian Chemical Communications
Journal Index: ISI
Volume: 4
Number: 11
Identification Number: https://doi.org/10.22034/ecc.2022.345173.1483
ISSN: 2717-0535
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3990

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