Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Investigating the effect of methylprednisolone pulse on treatment of back pain

Thu Feb 2 18:07:44 2023

(2022) Investigating the effect of methylprednisolone pulse on treatment of back pain. Eurasian Chemical Communications. pp. 366-371. ISSN 2717-0535

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Abstract

Pain is a common problem afflicting humanity. Back pain is a musculoskeletal disorder with a high prevalence; this pain may occur to anyone at least once during their lifetime. The present study was performed to investigate the effect of methylprednisolone pulse on the pain status of patients suffering from back pain in Ilam city. This double-blind study in 2021 in Ilam city with experimental and control. The patients with vertebral disc herniation diagnoses suffering from diffuse pain with the right leg were assigned into experimental and control groups. A methylprednisolone 500 mg IV would be administered to the patient as pulse inside DW 500 cc serum. The extent of pain was compared before and after the intervention at one, two, three, and seven days later. Placebo was applied for the control group patients. The data were analyzed by SPSS 16 and based on descriptive and analytical tests. Results showed no statistically significant difference between the demographic characteristics and pain of patients receiving methylprednisolone and patients in the control group(p<0.05). Also, the mean (SD) pain score in the experimental group was 6.59(0.88) before the intervention and 1.76(0.69) in the week after the intervention, which was statistically significant(P=0.000). While, the changes in the control group's score before intervention were 6.82(0.71), and after the intervention were 6.77(1.12) (P>0.05). Considering the effect of methylprednisolone on mitigating the pain of patients suffering from back pain, it is suggested to use injective methylprednisolone to reduce the pain of patients suffering from back pain.

Item Type: Article
Creators:
CreatorsEmail
Hatefi, M.UNSPECIFIED
Komlakh, K.UNSPECIFIED
Keywords: Methylprednisolone back pain drug therapy Chemistry
Divisions:
Page Range: pp. 366-371
Journal or Publication Title: Eurasian Chemical Communications
Journal Index: ISI
Volume: 4
Number: 5
Identification Number: https://doi.org/10.22034/ecc.2022.323514.1293
ISSN: 2717-0535
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3984

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