Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Evaluation of Laboratory Variables Related to Diffuse Axonal Injury: A Cross-Sectional Study

Thu Feb 2 18:10:35 2023

(2022) Evaluation of Laboratory Variables Related to Diffuse Axonal Injury: A Cross-Sectional Study. Archives of Neuroscience. p. 5. ISSN 2322-3944

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Abstract

Background: Diffuse axonal injury (DAI) is an injury that occurs after the onset of traumatic brain injury (TBI), leading to many problems for patients and imposing high costs on the treatment system. Objectives: This study was conducted to investigate the status of laboratory variables in patients with DAI. Methods: This cross-sectional study included 140 patients. Data collection tools were a demographic profile form and magnetic resonance imaging (MRI). Laboratory tests, including glucose, LDL-C, HDL-C, total cholesterol, triglycerides, Hb, HCT, PT, PTT, INR, BUN, creatinine, and CRP were evaluated. Also, specialized devices were used to study the laboratory and radiology variables. Results: Most (61.5) of the patients were male, 47.1 had a non-governmental occupation, and 55.7 were less than 30 years old. Also, in 87.9 of cases, traffic accidents were the cause of DAI and in 65 of patients, the Glasgow Coma Scale (GCS) was less than 7. In all the laboratory variables differences were observed between the experimental and the control groups. Conclusions: The laboratory variables in patients with DAI had a statistically significant difference compared to the case group, which indicates the negative effect of DAI on laboratory variables. Further studies are required to confirm our results.

Item Type: Article
Creators:
CreatorsEmail
Hatefi, M.UNSPECIFIED
Komlakh, K.UNSPECIFIED
Keywords: Diffuse Axonal Injury Laboratories Biomarker traumatic brain-injury epidemiology serum moderate Neurosciences & Neurology
Divisions:
Page Range: p. 5
Journal or Publication Title: Archives of Neuroscience
Journal Index: ISI
Volume: 9
Number: 3
Identification Number: https://doi.org/10.5812/ans-127451
ISSN: 2322-3944
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3982

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