Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

The frequency, related cause of disease, and treatment of hepatitis B virus infection: A systematic review and meta-analysis in Iran

Wed Feb 8 11:09:27 2023

(2022) The frequency, related cause of disease, and treatment of hepatitis B virus infection: A systematic review and meta-analysis in Iran. Journal of Research in Medical Sciences. p. 6. ISSN 1735-1995

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Abstract

Background: Hepatitis B virus (HBV) is one of the most dreadful viruses causing high mortality rates and serious damages to hepatocytes. The aim of this study was to assess the frequency, related causes/risk factors, and treatments of HBV infection in Iran by systematic review and meta-analysis. Materials and Methods: The data were obtained by a literature search in the PubMed, Scopus, SID, and Web of Sciences databases. Keywords included prevalence, risk factors, causes, treatment, and HBV. The Persian equivalents of these keywords were also searched. The time span included 2004 to2021. The Q and I2 statistics were used to check heterogeneity among studies. The data were analyzed using Stata (version 14). Results: The frequencies of HBV infection and its pharmaceutical therapy were P = 6 (95 confidence interval CI: 4-9, I2 = 95.2%, P < 0.001) and 19% (95% CI: 18%-30%, I2 = 98.9%, P < 0.001), respectively. The most common risk factors/causes of HBV were narcotic consumption, blood-related factors, and transmission from infected individuals with the respective frequencies of 27% (95% CI: 16%-38%, I2 = 88.7%, P < 0.001), 32% (95% CI: 11%-53%, I2 = 99.8%, P < 0.001), 25% (95% CI: 10%-41%, I2 = 99.3%, P < 0.001), and 15% (95% CI: 7%-22%, I2 = 98.4%, P < 0.001), respectively. Conclusion: The most important causes of HBV infection were transmission from infected people, narcotic consumption, and blood-related factors. The main therapeutic intervention for HBV was pharmaceutical therapy.

Item Type: Article
Creators:
CreatorsEmail
Kalvandi, G.UNSPECIFIED
Abangah, G.UNSPECIFIED
Veisani, Y.UNSPECIFIED
Nourmohammadi, H.UNSPECIFIED
Golitaleb, M.UNSPECIFIED
Tavan, H.UNSPECIFIED
Keywords: Hepatitis B virus frequency treatment meta-analysis residual risk blood-donors c virus prevalence hiv General & Internal Medicine
Divisions:
Page Range: p. 6
Journal or Publication Title: Journal of Research in Medical Sciences
Journal Index: ISI
Volume: 27
Number: 1
Identification Number: https://doi.org/10.4103/jrms.JRMS₆₇₁₉
ISSN: 1735-1995
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3929

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