Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Gastrointestinal Manifestations of the COVID-19: A Systematic Review and Meta-Analysis with 111 studies

Sun Nov 27 22:06:12 2022

(2021) Gastrointestinal Manifestations of the COVID-19: A Systematic Review and Meta-Analysis with 111 studies. Journal of Biostatistics and Epidemiology. pp. 321-343. ISSN 23834196 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Introduction: Since the start of a pandemic from Wuhan, China in 2019, there is tremendous attention on the COVID-19 manifestation. One of the most important COVID-19 clinical presentations is gastrointestinal symptoms. The current systematic review study aims to focus on the implication of the gastrointestinal tract in patients infected with SARS-CoV-2. Methods: We searched literature in MEDLINE, Scopus, Web of Science, and Embase to find related article by using the following keywords "COVID-19", "SARS-CoV-2 infection", "Gastrointestinal Tract", "digestive system". The heterogeneity of included studies was quantified with the I2 statistic. A random-effects model was used to estimate the pooled prevalence and a meta-regression method was utilized to investigate the factors affecting heterogeneity between studies. Results: Of 3028 retrieved documents, 111 studies with 21126 COVID-19 cases were included. The prevalence of any Gastrointestinal symptoms was 17.22 (14.48 to 20.13). The prevalence of diarrhea was 13.75 (12.07 to 15.44), anorexia 27.41 (21.53 to 33.29) and Nausea/vomiting 8.11 (6.87 to 9.35). Furthermore, the prevalence of other symptoms in current study was fever 76.70 (73.42 to 79.83), cough 58.07 (54.59 to 61.52) and dyspnea/shortness of breath 24.63 (20.06 to 29.48). According to meta-regression results, age (p: 0.027) and fever (p<0.001) had significant effect on prevalence of any Gastrointestinal symptoms. Conclusion: The anorexia, diarrhea, nausea, and vomiting are the most common Gastrointestinal presentations. Copyright © 2021 Tehran University of Medical Sciences.

Item Type: Article
Creators:
CreatorsEmail
Soltani, S.UNSPECIFIED
Zakeri, A.UNSPECIFIED
Pakzad, I.UNSPECIFIED
Tabibzadeh, A.UNSPECIFIED
Zakeri, A. M.UNSPECIFIED
Zandi, M.UNSPECIFIED
Rezayat, S. A.UNSPECIFIED
Jafarzadeh, M.UNSPECIFIED
Asl, P. K.UNSPECIFIED
Zebardast, A.UNSPECIFIED
Erfani, Y.UNSPECIFIED
Shahbahrami, R.UNSPECIFIED
Pakzad, R.UNSPECIFIED
Malekifar, P.UNSPECIFIED
Keywords: COVID-19 Gastrointestinal Tract Meta-Analysis SARS-CoV-2 Systematic Review
Divisions:
Page Range: pp. 321-343
Journal or Publication Title: Journal of Biostatistics and Epidemiology
Journal Index: Scopus
Volume: 7
Number: 4
ISSN: 23834196 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3891

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