Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Oral contraceptive pill and metabolic syndrome: Fasa Persian Cohort Study (Descriptive study)

Thu Oct 6 08:26:48 2022

(2022) Oral contraceptive pill and metabolic syndrome: Fasa Persian Cohort Study (Descriptive study). Diabetes & metabolic syndrome. p. 102408. ISSN 1878-0334 (Electronic) 1871-4021 (Linking)

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/35093686

Abstract

BACKGROUND AND AIMS: The contraceptive use is 56 and prevalence of metabolic syndrome (MetS) is 30 in Iran. The aim of this study investigates relationship between oral contraceptive pills (OCP) use and MetS in women in the cohort population of Fasa city. METHODS: In a cross-sectional study, 5489 women aged 35-70 years were studied for 5 years in the Sheshdeh area in 2016. MetS were calculated using adult treatment panel III (ATP III) and international diabetes federation (IDF) methods. The odds ratio (OR) with a 95 confidence interval (CI) was reported. Linear regression was used to eliminate the confounding effect. RESULTS: The OR of developing MetS in the OCP recipients was estimated as higher than the non-recipients. The OR of developing MetS using IDF criteria in OCP recipients was (OR = 0.896,95 CI:0.800-1.004). that increased to (OR = 1.230,95 CI:1.084-1.395) after adjusting for confounding variables. Also, the odds ratio using ATP (III) criteria was (OR = 0.900,95 CI:0.804-1.009). that increased to (OR = 1.245,95 CI:1.098-1.413) after adjusting for confounding variables. Also, the OR of developing MetS in OCP recipients decreased with increasing the number of MetS components from 1.199 to 0.812,95 CI:0.771-1.864,0.467-1.413, but after adjustment, increased from 1.151 to 1.747,95 CI:0.733-1.805,0.815-3.746. CONCLUSION: The results of the present study showed that the OR of developing MetS in OCP recipients using both IDF and ATP (III) methods was higher after adjusting by confounder effects so it is recommended monitoring by physicians.

Item Type: Article
Creators:
CreatorsEmail
Zareei, S.UNSPECIFIED
Behrasi, F.UNSPECIFIED
Naghizadeh, M. M.UNSPECIFIED
Talebzadeh, F.UNSPECIFIED
Kharmandar, A.UNSPECIFIED
Davoodi, S. H.UNSPECIFIED
Asadi, M.UNSPECIFIED
Farjam, M.UNSPECIFIED
Homayounfar, R.UNSPECIFIED
Keywords: Contraceptive pills Metabolic syndrome Moderator effect Pregnancy Women is original, that all statements asserted as facts are based on authors careful investigation and accuracy, that the manuscript has not been published in total or in part previously and has not been submitted or considered for publication in total or in part elsewhere. Each author acknowledges he/she has participated in the work in a substantive way and is prepared to take public responsibility for the work and authors have no competing interest to results of article.
Divisions:
Page Range: p. 102408
Journal or Publication Title: Diabetes & metabolic syndrome
Journal Index: Pubmed
Volume: 16
Number: 2
Identification Number: https://doi.org/10.1016/j.dsx.2022.102408
ISSN: 1878-0334 (Electronic) 1871-4021 (Linking)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3861

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