Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Evaluation of the therapeutic effect of the plasma of recovered COVID-19 patients for treating the patients admitted to the intensive care unit

Tue Aug 16 05:56:51 2022

(2021) Evaluation of the therapeutic effect of the plasma of recovered COVID-19 patients for treating the patients admitted to the intensive care unit. New Microbes and New Infections. p. 4.

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Abstract

The novel coronavirus has infected about 141 million people around the world. So far, about 80.4 million people have been discharged, and nearly 3.01 million people have died (an estimated mortality rate of 2.13). The study aimed to investigate the effect of plasma therapy from recovered COVID-19 patients to treat the patients hospitalized in the intensive care unit (ICU) of the Shahid Mostafa Khomeini Hospital of Ilam in 2020. The present prospective study was conducted in 2019-2020. Overall, 57 cases of plasma therapy were analysed using the Cox proportional hazard regression model in STATA 12 software. The results showed in patients receiving plasma treatment, the hazard ratio was (HR = 0.68, 95 CI, 0.45-1.04), indicating a 32 lower risk of death in the COVID-19 patients who received plasma therapy compared to those who did not. However, this relationship does not reach statistical significance (p = 0.07). Plasma therapy seems to yield some efficacy among patients with severe COVID-19 and those who have no underlying diseases. It is recommended to be used in combination with pharmaceutical interventions, for example, Actemra, to assess its therapeutic efficiency. (c) 2021 The Author(s). Published by Elsevier Ltd.

Item Type: Article
Creators:
CreatorsEmail
Ghaysouri, A.UNSPECIFIED
Nourmohammadi, H.UNSPECIFIED
Qasemi, E.UNSPECIFIED
Mozafari, A. A.UNSPECIFIED
Tavan, H.UNSPECIFIED
Saghari, S.UNSPECIFIED
Keywords: COVID-19 ICU lung involvement mortality plasma therapy Infectious Diseases Microbiology
Divisions:
Page Range: p. 4
Journal or Publication Title: New Microbes and New Infections
Journal Index: ISI
Volume: 44
Identification Number: https://doi.org/10.1016/j.nmni.2021.100941
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3670

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