Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

RISK OF COLORECTAL CANCER IN DEPRESSED PATIENTS, NEGATIVE LIFE EVENTS, AND THE PREVALENCE RATE OF DEPRESSIVE SYMPTOMS: A CASE-CONTROL STUDY

Wed Nov 30 17:22:05 2022

(2021) RISK OF COLORECTAL CANCER IN DEPRESSED PATIENTS, NEGATIVE LIFE EVENTS, AND THE PREVALENCE RATE OF DEPRESSIVE SYMPTOMS: A CASE-CONTROL STUDY. World Cancer Research Journal. p. 8. ISSN 2372-3416

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Abstract

Objective: This study aimed at investigating the risk of Colorectal Cancer (CRC) among depressed and Negative Life Events (NLEs) people and the prevalence of depressive symptoms. Materials and Methods: A case-control study was performed from the Colonoscopy Unit of the Cancer Institute in Tabriz. A total of 207 cases with confirmed pathology findings and 207 controls, at the same time for the cases, were included. Multiple logistic regression was used to estimate the adjusted odds ratios and 95 confidence intervals. Results: In the final multiple variable models, depression was associated with CRC insignificantly (OR=1.42, 95 CI: 0.92-2.21); however, NLEs were associated with CRC risk (OR=1.84, 95 CI: 1.08-3.16). Likewise, family history of CRC, diabetes, and smoking were associated with an elevated risk of CRC. Moreover, the prevalence rate () of depressive symptoms among cases and controls was revealed as 11-8 severe, 19-14 moderate, 27-24 mild and 43-54 minimal, respectively. Conclusions: There was a significant positive association between CRC and NLEs while no evidence found that depression increases the risk of CRC.

Item Type: Article
Creators:
CreatorsEmail
Azizi, H.UNSPECIFIED
Esmaeili, E. D.UNSPECIFIED
Sayehmiri, K.UNSPECIFIED
Karimi, G.UNSPECIFIED
Asadollahi, K.UNSPECIFIED
Keywords: Depression Colorectal cancer Negative life events Case-control Tabriz health questionnaire natural-history mortality association predictors validity Oncology
Divisions:
Page Range: p. 8
Journal or Publication Title: World Cancer Research Journal
Journal Index: ISI
Volume: 8
ISSN: 2372-3416
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3612

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