Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Effectiveness of maggot extractions and secretion (E/S) of Lucilia sericata in reducing wound surface in experimental scalding burn injury

Sun Sep 25 12:04:47 2022

(2021) Effectiveness of maggot extractions and secretion (E/S) of Lucilia sericata in reducing wound surface in experimental scalding burn injury. Nusantara Bioscience. pp. 11-15. ISSN 2087-3948

Full text not available from this repository.

Official URL: http://apps.webofknowledge.com/InboundService.do?F...

Abstract

Lucilia sericata larvae have been successfully used as medicinal larvae for wound healing. This study was performed to evaluate the therapeutic effects of the primary ointment made from excretory-secretory substances of L. sericata larvae on experimental bum wounds on rabbits under laboratory conditions. Extraction of ES from the third stage of L. sericata larvae and antibiogram testing was done. Four rabbits were randomly divided into four groups; three standard third-grade bum wounds were created on the back of each rabbit for intervention groups (B, D) of wounds were used respectively from the original ointment made from ES and ES without accompanying material. Nitrofurazone ointment was used for the positive (C) and placebo ointment was used for the negative (A). On the 21st day, all scars of wounds in groups B and D were separated and the wound was free of infectious tissue, whereas in groups A and C that the scars were clinging to the base. The level of the ulcer was significantly lower in the E/S intervention group and the infectious tissue was not observed during the treatment of group B and D wounds. Methicillin-resistant Staphylococcus aureus (MRSA) did not show resistance to excretory-secretory substances of L. sericata larvae. The debridement and recovery process was faster in the ES-treated group and the initial ointment than in the control group. The results showed that maggot extractions and secretion (E/S) of L. sericata in reducing wound healing is appropriate for treatment.

Item Type: Article
Creators:
CreatorsEmail
Amiri, Z. S.UNSPECIFIED
Akbarzadeh, K.UNSPECIFIED
Douraghi, M.UNSPECIFIED
Abdi, K. M.UNSPECIFIED
Afshar, A. A.UNSPECIFIED
Ghaffari, J.UNSPECIFIED
Kordshouli, R. S.UNSPECIFIED
Akbari, M.UNSPECIFIED
Rafinejad, J.UNSPECIFIED
Keywords: Burn Lucilia sericata ointment secretion-excretion wounds larval secretions in-vitro therapy infections diptera Life Sciences & Biomedicine - Other Topics
Divisions:
Page Range: pp. 11-15
Journal or Publication Title: Nusantara Bioscience
Journal Index: ISI
Volume: 13
Number: 1
Identification Number: https://doi.org/10.13057/nusbiosci/n130102
ISSN: 2087-3948
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3608

Actions (login required)

View Item View Item