Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

A review of the most important native medicinal plants of Iran effective on cutaneous Leishmaniasis in mouse model

Mon Dec 2 13:59:01 2024

(2017) A review of the most important native medicinal plants of Iran effective on cutaneous Leishmaniasis in mouse model. Pharmaceutical Bioprocessing. pp. 28-32. ISSN 2048-9145

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Abstract

Leishmaniasis is a zoonotic parasitic disease that is caused by different Leishmania species. Most cases of Leishmaniasis are reported from Afghanistan, Saudi Arabia, Algeria, Brazil, Iraq, and Iran. Antimony compounds have long been used as standard treatment and first line drugs for Leishmaniasis, but Leishmania species have recently acquired drug resistance. Nowadays, medicinal plants are being increasingly used to treat parasitic diseases especially Leishmaniasis. In this review, the search terms Leishmania, Leishmaniasis, mouse, Iran, and medicinal plants were used to retrieve publications from databases such as Scopus, Islamic World Science Citation Center, Scientific Information Database, and Magiran. According to the results of this review, nine medicinal plants, Eucalyptus camaldulensis, Matricaria chamomilla, Cathrantus roseus, Echinacea purpurea, Lawsonia inermis, Artemisia sieberi, Berberis vulgaris, Allium sativum L., and Lavandula spica L. have been reported to be effective on Leishmaniasis wound in mouse model. Lawson, berberine, jatrorrhizine, colombamine, palmatine, oxyacanthine, berbamine, berulicin, magnoflorine, allicin, eucalyptol, paracymene, alpha-pinene, caffeic acids, alkylamides, echinacosides, glycoproteins, polysaccharide, chamazulene, pigenin, trihydroxyflavone, and patholiterin, berberrubine, flavonoid compounds, santonin, and coumarin are the active compounds of the native medicinal plants of Iran that are effective on Leishmaniasis wound.

Item Type: Article
Creators:
CreatorsEmail
Shahsavari, S.UNSPECIFIED
Rafieian-Ko-Paei, M.UNSPECIFIED
Keywords: mouse leishmaniasis medicinal plants Iran allium-sativum chemical-composition phenolic-compounds limnatis-nilotica controlled-trial essential oils extract hydrocarbons microwave echinacea Biotechnology & Applied Microbiology
Divisions:
Page Range: pp. 28-32
Journal or Publication Title: Pharmaceutical Bioprocessing
Journal Index: ISI
Volume: 5
Number: 3
ISSN: 2048-9145
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/354

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