Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

The global survival rate of patients with beta-thalassemia major: A systematic review and meta-analysis

Tue Aug 16 12:26:04 2022

(2021) The global survival rate of patients with beta-thalassemia major: A systematic review and meta-analysis. Journal of Contemporary Medical Sciences. pp. 80-85. ISSN 2413-0516

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Abstract

Objective Thalassemia is a public health challenge in the countries entitled belt thalassemia, but there is no pooled estimate of the survival rate on thalassemia major patients.The aim of this meta-analysis was to evaluate the pooled 10-, 15-, 20-, and 30-year survival rates of the patients with beta-thalassemia major around the world. Methods A comprehensive literature search of five international databases including Medline/PubMed, Scopus, Embase, Web of knowledge, and ProQuest was conducted to identify studies reporting survival rate of beta-thalassemia major until March 2020. Results From 714 retrieved studies, 7 studies with 8777 subjects were included in the meta-analysis. Base on random effect model, the 10-, 15-, 20-, and 30-year survival rates were 98.39, 95.07, 90.41, and 82.93 percent, respectively. Conclusions This meta-analysis provided acceptable results for estimating survival rate of beta-thalassemia compared to other studies. Hence, these results can be effectively used to develop and implement prevention and treatment interventions for policymakers.

Item Type: Article
Creators:
CreatorsEmail
Soltani, M.UNSPECIFIED
Hassanipour, S.UNSPECIFIED
Veisani, Y.UNSPECIFIED
Darbandi, M.UNSPECIFIED
Rezaiean, S.UNSPECIFIED
Keywords: Survival rate Beta-thalassemia major Systematic review Meta-analysis chelation-therapy asian countries complications transplantation General & Internal Medicine
Divisions:
Page Range: pp. 80-85
Journal or Publication Title: Journal of Contemporary Medical Sciences
Journal Index: ISI
Volume: 7
Number: 2
Identification Number: https://doi.org/10.22317/jcms.v7i2.903
ISSN: 2413-0516
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3459

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