Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Neutrophil-to-Lymphocyte Ratio as a Poor Prognostic Factor in Iranian COVID-19 Patients

Fri Aug 19 04:09:30 2022

(2021) Neutrophil-to-Lymphocyte Ratio as a Poor Prognostic Factor in Iranian COVID-19 Patients. Clinical Laboratory. pp. 370-375. ISSN 14336510 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Background: We aimed to accumulate evidence that suggests the potential role of neutrophil-to-lymphocyte ratio (NLR) in determining the prognostic factor for COVID-19 patients. Methods: A cohort of COVID-19 hospitalized patients at the Ilam University of Medical Sciences was analyzed. Logistic regression models were performed to identify the potential role of NLR in determining the prognostic factor for COVID-19 patients. Results: The total number of in-hospital mortality was 43/328 (13.1). Multivariate analysis identified that there was a 26 higher risk of in-hospital death for each unit increase in NLR (Odds ratio OR = 1.08; 95% confidence interval 95% CI, 1.01 to 1.14; p = 0.0147). Multivariate analysis identified that there was an 8% higher risk of in-hospital death for each unit increase in NLR (Odds ratio OR = 1.08; 95% confidence interval 95% CI, 1.01 to 1.14; p = 0.0147). Compared with patients in the NLR < 5 group, the NLR of patients in the NLR ≥ 5 group had a 16-fold higher risk of mortality (OR = 16.04; 95% CI, 1.14 to 224.95; p = 0.0395) after adjustment for potential confounders. Conclusions: NLR is an independent risk factor of mortality COVID-19 patients. © 2021 Verlag Klinisches Labor GmbH. All rights reserved.

Item Type: Article
Creators:
CreatorsEmail
Kouhsari, E.UNSPECIFIED
Sadeghifard, N.UNSPECIFIED
Karimian, M.UNSPECIFIED
Sayyadi, H.UNSPECIFIED
Nazari, A.UNSPECIFIED
Mozafari, A. A.UNSPECIFIED
Kazemian, H.UNSPECIFIED
Valadbeigi, H.UNSPECIFIED
Kaffashian, M. R.UNSPECIFIED
Keywords: COVID-19 Neutrophil-to-lymphocyte ratio Poor prognosis hemoglobin adolescent adult aged Article child cohort analysis confounding variable controlled study coronavirus disease 2019 electronic health record erythrocyte count erythrocyte sedimentation rate female hematocrit hospital mortality hospital patient human Iranian (citizen) laboratory test leukocyte count logistic regression analysis major clinical study male mortality risk multivariate analysis neutrophil lymphocyte ratio nose smear platelet count prognosis retrospective study risk factor throat swab urea nitrogen blood level blood diagnosis epidemiology hospitalization Iran isolation and purification lymphocyte middle aged mortality neutrophil procedures risk assessment therapy Humans Lymphocytes Neutrophils Retrospective Studies Risk Factors SARS-CoV-2
Divisions:
Page Range: pp. 370-375
Journal or Publication Title: Clinical Laboratory
Journal Index: Scopus
Volume: 67
Number: 2
Identification Number: https://doi.org/10.7754/Clin.Lab.2020.200726
ISSN: 14336510 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3400

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