Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Comparing the effect of herbal drugs and non-steroidal anti-inflammatory drugs on primary dysmenorrhea in iran: A systematic review and meta-analysis

Thu Aug 18 13:17:51 2022

(2021) Comparing the effect of herbal drugs and non-steroidal anti-inflammatory drugs on primary dysmenorrhea in iran: A systematic review and meta-analysis. Journal of Chemical Health Risks. pp. 41-53. ISSN 22516719 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Several studies have been conducted to investigate the effects of herbal drugs and Non-steroidal anti-inflammatory drugs on the primary dysmenorrhea, but their results have been different.The aim of this study was to compare the effects of herbal drugs and NSAIDon the primary dysmenorrheausing meta-analysis method.A literature search was conducted in Scopus, Pub med, and Google scholar databases from1996 to December 2016 in English and Persian languages using the search keywordsof primary dysmenorrhea combined with herbal and NSAID. The random effect model was adoptedto combine the results of the studies, and I2 index was used to check heterogeneity. One hundred and ninety-nine studies were obtained, and after reading the abstracts, 21 articles were included in the study. The total number of samples was 2041 people. The standard mean difference(SMD)betweenherbal drugs and Non-steroidal anti-inflammatory drugs in the pain reduction in the first intervention was estimated atSMD= 0.2(95CI:(-0.340.74), z=0.73, p=0.463), and in second intervention it was SMD=-0.59(95CI: (-1.650.47),Z=1.09 and p=0.278). also, the SMD for the duration of menstrual variable SMD=0.18(95CI:(0.02 0.34), z=2.20, p=0.027) in favor of NSAID drugs and interval cycle of menstrual variable was SMD=0.07(95CI:(-0.140.28), z=0.68, p=0.496).Mean difference of pain intensity reduced relatively better by administering herbal medicines, which is supported by the majority of studies, and the herbal drugs were found to be more effective than the NSAIDs drugs. Finally, given the many side effects of non-steroidal anti-inflammatory drugs, herbal drugs can be used at the standard dosageand considering the side effects. © 2021, Islamic Azad University. All rights reserved.

Item Type: Article
Creators:
CreatorsEmail
Chehreh, R.UNSPECIFIED
Sayemiri, K.UNSPECIFIED
Shohani, M.UNSPECIFIED
Vahidnia, S.UNSPECIFIED
Tavan, H.UNSPECIFIED
Keywords: Dysmenorrheal Herbal drugs Non-steroidal Anti-Inflammatory Drugs
Divisions:
Page Range: pp. 41-53
Journal or Publication Title: Journal of Chemical Health Risks
Journal Index: Scopus
Volume: 11
Number: 1
Identification Number: https://doi.org/10.22034/jchr.2020.1882587.1061
ISSN: 22516719 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3391

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