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Repository of Research and Investigative Information

Ilam University of Medical Sciences

Clinical, epidemiological, laboratory, and radiological characteristics of novel Coronavirus (2019-nCoV) in retrospective studies: A systemic review and meta-analysis

Tue Aug 16 06:20:57 2022

(2021) Clinical, epidemiological, laboratory, and radiological characteristics of novel Coronavirus (2019-nCoV) in retrospective studies: A systemic review and meta-analysis. Indian journal of medical microbiology. pp. 104-115. ISSN 1998-3646 (Electronic) 0255-0857 (Linking)

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/33610239

Abstract

BACKGROUND: In December 2019, a novel pneumonia related to the 2019 coronavirus unexpectedly developed in Wuhan, China. We aimed to review data of the novel Coronavirus (2019-nCoV) by analyzing all the published retrospective studies on the clinical, epidemiological, laboratory, and radiological characteristics of patients with 2019-nCoV. METHODS: We searched in four bibliographic databases PubMed, Scopus, Embase, and Web of Science) for studies March 10, 2020 focused on the clinical, epidemiological, laboratory, and radiological characteristics of patients with 2019-nCoV for meta-analysis. The Newcastle-Ottawa Scale was used to quality assessment, and publication bias was analyzed by Egger's test. In the meta-analysis, a random-effects model with Stata/SE software, v.14.1 (StataCorp, College Station, TX) was used to obtain a pooled incidence rate. RESULTS: Fifty studies were included in this systematic review and meta-analysis with 8815 patients and the mean age was 46 years and 4647 (52.7) were male. The pooled incidences rate of clinical symptoms were: fever (83, 95 CI: 0.77, 0.89), cough (59, 95 CI: 0.48, 0.69), myalgia or fatigue (31, 95 CI: 0.23, 0.39), sputum production (29, 95 CI: 0.21, 0.39), and dyspnea (19, 95 CI: 0.12, 0.26). The pooled incidence rate of acute respiratory distress syndrome (ARDS) was (22, 95 CI: 0.00, 0.60). CONCLUSION: The results of this systemic review and meta-analysis present a quantitative pooled incidence rate of different characters of 2019-nCoV and has great potential to develop diagnosis and patient's stratification in 2019-nCoV. However, this conclusions of this study still requisite to be warranted by more careful design, larger sample size multivariate studies to corroborate the results of this meta-analysis.

Item Type: Article
Creators:
CreatorsEmail
Kouhsari, E.UNSPECIFIED
Azizian, K.UNSPECIFIED
Sholeh, M.UNSPECIFIED
Shayestehpour, M.UNSPECIFIED
Hashemian, M.UNSPECIFIED
Karamollahi, S.UNSPECIFIED
Yaghoubi, S.UNSPECIFIED
Sadeghiifard, N.UNSPECIFIED
Keywords: Adult Aged COVID-19/*diagnosis/*epidemiology/*virology Disease Management Female Global Health Humans Male Middle Aged Public Health Surveillance Publication Bias Radiography Retrospective Studies *SARS-CoV-2 Symptom Assessment 2019-nCoV Clinical Epidemiological Laboratory, and radiological characteristics Meta-analysis of interests.
Divisions:
Page Range: pp. 104-115
Journal or Publication Title: Indian journal of medical microbiology
Journal Index: Pubmed
Volume: 39
Number: 1
Identification Number: https://doi.org/10.1016/j.ijmmb.2020.10.004
ISSN: 1998-3646 (Electronic) 0255-0857 (Linking)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3368

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