Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Investigating the relationship between low serum cholesterol and suicide in attempters with depression

Thu Dec 1 17:30:23 2022

(2020) Investigating the relationship between low serum cholesterol and suicide in attempters with depression. Journal of Advances in Medical and Biomedical Research. pp. 323-329. ISSN 26766264 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Background & Objective: It has been postulated that depressed individuals with low total cholesterol levels may be more likely to die prematurely from suicide. This study aimed to examine the association between low serum cholesterol and suicide in depressed attempters. Materials & Methods: In this cross-sectional study, 180 suicide attempters, who met the inclusion criteria and were willing to participate in the study, were recruited in 2017. The data was collected using a demographic questionnaire and the Beck Depression Inventory-Second Edition (BDI-II). The blood cholesterol level was measured via an auto-analyzer. Results: The mean age was 26.39±10.75 years. The average cholesterol level in the moderate, severe, and serious depression groups was 151.30±35.23, 145.89±36.32, and 145.15±33.33, respectively. The mean age was higher in the group with a higher depression level, though the difference was not significant (P=0.06). The percentage of suicide attempts in single individuals was significantly higher (P=0.02). The mean cholesterol level in the group with the highest level of depression was the lowest, but the difference was insignificant (r=-.01, P=0.85). Only in females, the level of blood cholesterol showed a nearly significant difference between groups with different severities of depression (P=0.05). Cholesterol had a significant correlation with suicide frequency (P=0.008, r=0.28). Conclusion: Our results revealed no significant association between low serum cholesterol and suicide in attempters with depression; but low total serum cholesterol may be associated with depression and suicide in depressed subjects. Yet, more studies are required for verification of this causality. © 2020, Journal of Advances in Medical and Biomedical Research. All rights reserved.

Item Type: Article
Creators:
CreatorsEmail
Aghakhani, N.UNSPECIFIED
Boushehri, B.UNSPECIFIED
Zarei, A.UNSPECIFIED
Roshani, R.UNSPECIFIED
Nazimi, N.UNSPECIFIED
Cheraghi, R.UNSPECIFIED
Sayyadi, H.UNSPECIFIED
Vahabzadeh, D.UNSPECIFIED
Keywords: Attempter Depression Serum cholesterol Suicide cholesterol adolescent adult Article Beck Depression Inventory cholesterol blood level cross-sectional study female hospitalization human human experiment male prevalence questionnaire suicide attempt
Divisions:
Page Range: pp. 323-329
Journal or Publication Title: Journal of Advances in Medical and Biomedical Research
Journal Index: Scopus
Volume: 28
Number: 131
Identification Number: https://doi.org/10.30699/jambs.28.131.323
ISSN: 26766264 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3300

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