Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Mon Oct 14 06:10:47 2024

(2020) Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet. pp. 1204-1222. ISSN 01406736 (ISSN)

Full text not available from this repository.

Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods: GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. Findings: Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990–2010 time period, with the greatest annualised rate of decline occurring in the 0–9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10–24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10–24 years were also in the top ten in the 25–49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50–74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. Interpretation: As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and developm nt investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve. Funding: Bill & Melinda Gates Foundation. © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license

Item Type: Article
Creators:
CreatorsEmail
Abbafati, C.UNSPECIFIED
Machado, D. B.UNSPECIFIED
Cislaghi, B.UNSPECIFIED
Salman, O. M.UNSPECIFIED
Karanikolos, M.UNSPECIFIED
McKee, M.UNSPECIFIED
Abbas, K. M.UNSPECIFIED
Brady, O. J.UNSPECIFIED
Larson, H. J.UNSPECIFIED
Trias-Llimós, S.UNSPECIFIED
Cummins, S.UNSPECIFIED
Langan, S. M.UNSPECIFIED
Sartorius, B.UNSPECIFIED
Hafiz, A.UNSPECIFIED
Jenabi, E.UNSPECIFIED
Mohammad Gholi Mezerji, N.UNSPECIFIED
Borzouei, S.UNSPECIFIED
Azarian, G.UNSPECIFIED
Khazaei, S.UNSPECIFIED
Abbasi, M.UNSPECIFIED
Asghari, B.UNSPECIFIED
Masoumi, S.UNSPECIFIED
Komaki, H.UNSPECIFIED
Taherkhani, A.UNSPECIFIED
Adabi, M.UNSPECIFIED
Abbasifard, M.UNSPECIFIED
Bazmandegan, G.UNSPECIFIED
Kamiab, Z.UNSPECIFIED
Vakilian, A.UNSPECIFIED
Anjomshoa, M.UNSPECIFIED
Mokari, A.UNSPECIFIED
Sabour, S.UNSPECIFIED
Shahbaz, M.UNSPECIFIED
Saeedi, R.UNSPECIFIED
Ahmadieh, H.UNSPECIFIED
Yousefinezhadi, T.UNSPECIFIED
Haj-Mirzaian, A.UNSPECIFIED
Nikbakhsh, R.UNSPECIFIED
Safi, S.UNSPECIFIED
Asgari, S.UNSPECIFIED
Irvani, S. N.UNSPECIFIED
Jahanmehr, N.UNSPECIFIED
Ramezanzadeh, K.UNSPECIFIED
Abbasi-Kangevari, M.UNSPECIFIED
Khayamzadeh, M.UNSPECIFIED
Abbastabar, H.UNSPECIFIED
Shirkoohi, R.UNSPECIFIED
Fazlzadeh, M.UNSPECIFIED
Janjani, H.UNSPECIFIED
Hosseini, M.UNSPECIFIED
Mansournia, M.UNSPECIFIED
Tohidinik, H.UNSPECIFIED
Bakhtiari, A.UNSPECIFIED
Fazaeli, A.UNSPECIFIED
Mousavi, S.UNSPECIFIED
Hasanzadeh, A.UNSPECIFIED
Nabavizadeh, B.UNSPECIFIED
Malekzadeh, R.UNSPECIFIED
Hashemian, M.UNSPECIFIED
Pourshams, A.UNSPECIFIED
Salimzadeh, H.UNSPECIFIED
Sepanlou, S. G.UNSPECIFIED
Afarideh, M.UNSPECIFIED
Esteghamati, A.UNSPECIFIED
Esteghamati, S.UNSPECIFIED
Ghajar, A.UNSPECIFIED
Heidari, B.UNSPECIFIED
Rezaei, N.UNSPECIFIED
Mohamadi, E.UNSPECIFIED
Rahimi-Movaghar, A.UNSPECIFIED
Rahim, F.UNSPECIFIED
Eskandarieh, S.UNSPECIFIED
Sahraian, M.UNSPECIFIED
Mohebi, F.UNSPECIFIED
Aminorroaya, A.UNSPECIFIED
Ebrahimi, H.UNSPECIFIED
Farzadfar, F.UNSPECIFIED
Mohajer, B.UNSPECIFIED
Pishgar, F.UNSPECIFIED
Saeedi Moghaddam, S.UNSPECIFIED
Shabani, M.UNSPECIFIED
Zarafshan, H.UNSPECIFIED
Abolhassani, H.UNSPECIFIED
Hafezi-Nejad, N.UNSPECIFIED
Heidari-Soureshjani, R.UNSPECIFIED
Abdollahi, M.UNSPECIFIED
Farahmand, M.UNSPECIFIED
Salamati, P.UNSPECIFIED
Mehrabi Nasab, E.UNSPECIFIED
Tajdini, M.UNSPECIFIED
Aghamir, S.UNSPECIFIED
Mirzaei, R.UNSPECIFIED
Dibaji Forooshani, Z.UNSPECIFIED
Khater, M. M.UNSPECIFIED
Abd-Allah, F.UNSPECIFIED
Abdelalim, A.UNSPECIFIED
Abualhasan, A.UNSPECIFIED
El-Jaafary, S. I.UNSPECIFIED
Hassan, A.UNSPECIFIED
Elsharkawy, A.UNSPECIFIED
othersUNSPECIFIED
Divisions:
Page Range: pp. 1204-1222
Journal or Publication Title: The Lancet
Journal Index: Scopus
Volume: 396
Number: 10258
Identification Number: https://doi.org/10.1016/S0140-6736(20)30925-9
ISSN: 01406736 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3279

Actions (login required)

View Item View Item