Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Decorated Au NPs on agar modified Fe3O4 NPs: Investigation of its catalytic performance in the degradation of methylene orange, and anti-human breast carcinoma properties

Sat Jun 15 04:07:25 2024

(2020) Decorated Au NPs on agar modified Fe3O4 NPs: Investigation of its catalytic performance in the degradation of methylene orange, and anti-human breast carcinoma properties. International journal of biological macromolecules. pp. 787-795. ISSN 1879-0003 (Electronic) 0141-8130 (Linking)

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/32980407

Abstract

This work describes an eco-friendly approach for in situ immobilization of Au nanoparticles on the surface of Fe3O4 nanoparticles, with help of Agar and ultrasound irradiations, without using any toxic reducing and capping agents. The structure, morphology, and physicochemical properties were characterized by various analytical techniques such as Fourier transformed infrared spectroscopy (FT-IR), field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), energy dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD), inductively coupled plasma (ICP) and vibrating sample magnetometer (VSM). The desired catalyst showed great efficiency in the reductive degradation of methylene orange (MO) dye over NaBH4 at room temperature. The MO was fully reduced in only 70 s and achieved rate constant of 9.6 x 10(-2) s(-1). The catalyst was reused for 10 runs without significant loss in catalytic activity. Cell viability of Fe3O4/agar/Au NPs was very low against breast adenocarcinoma (MCF7), breast carcinoma (Hs 578Bst), infiltrating ductal cell carcinoma (Hs 319.T), and metastatic carcinoma (MDA-MB-453) cell lines without any cytotoxicity on the normal cell line. According to the above findings, the Fe3O4/agar/Au NPs may be administrated for the treatment of several types of human breast carcinoma in humans.

Item Type: Article
Creators:
CreatorsEmail
Sun, T.UNSPECIFIED
Gao, J.UNSPECIFIED
Shi, H.UNSPECIFIED
Han, D.UNSPECIFIED
Zangeneh, M. M.UNSPECIFIED
Liu, N.UNSPECIFIED
Liu, H.UNSPECIFIED
Guo, Y.UNSPECIFIED
Liu, X.UNSPECIFIED
Keywords: Gold nanoparticles Human breast carcinoma Methylene orange
Divisions:
Page Range: pp. 787-795
Journal or Publication Title: International journal of biological macromolecules
Journal Index: Pubmed
Volume: 165
Number: Pt A
Identification Number: https://doi.org/10.1016/j.ijbiomac.2020.09.157
ISSN: 1879-0003 (Electronic) 0141-8130 (Linking)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3263

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