Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Seroprevalence of Hepatitis E Virus infection among pregnant women in Ilam, west of Iran

Fri May 31 01:20:59 2024

(2020) Seroprevalence of Hepatitis E Virus infection among pregnant women in Ilam, west of Iran. Infectious disorders drug targets. ISSN 2212-3989 (Electronic) 1871-5265 (Linking)

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/33155920

Abstract

INTRODUCTION: Hepatitis E infection is commonly known as acute and self-limiting hepatitis and therefore less at-tention is paid to it, whereas hepatitis E virus is a major cause of fulminant hepatitis in pregnant women and its infection during pregnancy is associated with maternal and fetal mortality. The prevalence of anti-HEV antibodies in pregnant women in Ilam city is unknown, the aim of the present study was to investigate the prevalence of anti- HEV total and anti-HEV IgM antibodies among pregnant women in this area. MATERIAL AND METHODS: A total of 420 serum samples were collected between March 2018 and September 2019 from preg-nant women, with a mean age of 29.61 years ranging from 19 to 47 years, referred to Ilam health centers, west of Iran. De-mographic data including age and place of residence were collected from patient records. The titers of anti-HEV total and anti-HEV IgM antibodies were measured by ELISA method. The association between the prevalence of hepatitis E antibody and age and place of residence variables was evaluated by chi-square test. Statistical analysis was performed using SPSS version 20. RESULTS: In total, 18 of the 420 participants (4.3) were positive for anti-HEV total, while 2 (0/47) tested positive for anti-HEV immunoglobulins M (IgM). Anti-HEV status had no statistically significant association with age and place of resi-dence. CONCLUSION: The seroprevalence rate of HEV infection among pregnant women in Ilam city is relatively low. Considering that seronegative pregnant women is at risk for acquiring HEV, it is recommended that pregnant women be educated to avoid sources of HEV infection.

Item Type: Article
Creators:
CreatorsEmail
Kenarkoohi, A.UNSPECIFIED
Falahi, S.UNSPECIFIED
Ghelijie, F.UNSPECIFIED
Mirzaei, A.UNSPECIFIED
Keywords: Epidemiology Hepatitis E virus Ilam Iran. Pregnant women Seroprevalence
Divisions:
Journal or Publication Title: Infectious disorders drug targets
Journal Index: Pubmed
Identification Number: https://doi.org/10.2174/1871526520999201103193321
ISSN: 2212-3989 (Electronic) 1871-5265 (Linking)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3254

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