Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Sub-minimum inhibitory concentrations of biocides induced biofilm formation in Pseudomonas aeruginosa

Wed Nov 30 08:00:54 2022

(2020) Sub-minimum inhibitory concentrations of biocides induced biofilm formation in Pseudomonas aeruginosa. New Microbes and New Infections. p. 100794. ISSN 2052-2975 (Print) 2052-2975 (Linking)

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/33240514

Abstract

It is clear that biofilm formation causes many serious health-care problems. Interestingly, sub minimum inhibitory concentrations (sub-MICs) of some biocides can induce biofilm formation in bacteria. We investigated whether sub-MICs of Savlon, chlorhexidine and deconex(R), as biocidal products, can induce biofilm formation in clinical isolates of Pseudomonas aeruginosa. To determine MICs and biofilm formation, we performed microtitre plate assays. All three biocides induced biofilm formation at sub-MICs; Savlon was the most successful antiseptic agent to induce biofilm formation among P. aeruginosa isolates. Deconex had the best inhibition effect on planktonic cultures of P. aeruginosa isolates. We concluded that sub-MICs of Savlon and deconex could significantly induce biofilm formation.

Item Type: Article
Creators:
CreatorsEmail
Hemati, S.UNSPECIFIED
Kouhsari, E.UNSPECIFIED
Sadeghifard, N.UNSPECIFIED
Maleki, A.UNSPECIFIED
Omidi, N.UNSPECIFIED
Mahdavi, Z.UNSPECIFIED
Pakzad, I.UNSPECIFIED
Keywords: Biofilm formation Pseudomonas aeruginosa biocides sub-MIC
Divisions:
Page Range: p. 100794
Journal or Publication Title: New Microbes and New Infections
Journal Index: Pubmed
Volume: 38
Identification Number: https://doi.org/10.1016/j.nmni.2020.100794
ISSN: 2052-2975 (Print) 2052-2975 (Linking)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3240

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