Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Determinants of delay in diagnosis and end stage at presentation among breast cancer patients in Iran: a multi-center study

Mon Jun 27 16:29:17 2022

(2020) Determinants of delay in diagnosis and end stage at presentation among breast cancer patients in Iran: a multi-center study. Scientific Reports. p. 21477. ISSN 2045-2322 (Electronic) 2045-2322 (Linking)

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/33293634

Abstract

One of the reasons for high mortality of breast cancer (BC) is long delay in seeking medical care and end stage at presentation. This study was designed to measure the association between a wide range of socio-demographic and clinical factors with diagnostic delay in BC and stage at presentation among Iranian patients. From June 2017 to December 2019, 725 patients with newly diagnosed BC in Shiraz and Kermanshah were selected and information on BC diagnosis delay was obtained from the patient's medical record. Data on socio-economic status was obtained via a structured interview. Our findings suggest that 45.8 of the patients were diagnosed at a late stage (stage 3 or higher). A total of 244 (34) patients had more than 3 months delay in diagnosis. We found a significant association between stage at diagnosis and place of residence (adjusted odds ratio (aOR rural vs. urban = 1.69, 95 CI 1.49-1.97), marital status (aOR 1.61, 95 CI 1.42-1.88), family history of BC (aOR 1.46, 95 CI 1.01-2.13), and history of benign breast disease (BBD) (aOR 1.94, 95 CI 1.39-2.72) or unaware of breast self-examination (BSE) (aOR 1.42, 95 CI 1.42-1.85), delay time (aOR 3.25, 95 CI 1.04-5.21), and left breast tumor (aOR right vs. left 2.64, 95 CI 1.88-3.71) and smoking (aOR no vs. yes 1.59, 95 CI 1.36-1.97). Also, delay in diagnosis was associated with age, family income, health insurance, place of residence, marital status, menopausal status, history of BBD, awareness of breast self-examination, type of first symptoms, tumor histology type, BMI and comorbidity (p < 0.05 for all). Factors including history of BBD, awareness of BSE, and suffering from chronic diseases were factors associated with both delay in diagnosis and end stage of disease. These mainly modifiable factors are associated with the progression of the disease.

Item Type: Article
Creators:
CreatorsEmail
Foroozani, E.UNSPECIFIED
Ghiasvand, R.UNSPECIFIED
Mohammadianpanah, M.UNSPECIFIED
Afrashteh, S.UNSPECIFIED
Bastam, D.UNSPECIFIED
Kashefi, F.UNSPECIFIED
Shakarami, S.UNSPECIFIED
Dianatinasab, M.UNSPECIFIED
Divisions:
Page Range: p. 21477
Journal or Publication Title: Scientific Reports
Journal Index: Pubmed
Volume: 10
Number: 1
Identification Number: https://doi.org/10.1038/s41598-020-78517-6
ISSN: 2045-2322 (Electronic) 2045-2322 (Linking)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3235

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