Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

The effects of multi mineral-vitamin D and vitamins (C+E) supplementation in the prevention of preeclampsia: An RCT

Fri Apr 19 13:39:38 2024

(2017) The effects of multi mineral-vitamin D and vitamins (C+E) supplementation in the prevention of preeclampsia: An RCT. International Journal of Reproductive Biomedicine. pp. 273-278. ISSN 2476-4108

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Abstract

Background: Several studies have reported the uncertain role of multi-minerals and vitamins in the prevention of preeclampsia. Objective: The present study aims to investigate the effect of multimineral-vitamin D supplements (calcium, magnesium, zinc and Vitamin D) and vitamins (C+E) in the prevention of preeclampsia. Materials and Methods: In this randomized clinical trial, 90 pregnant women were divided into three groups: group A received Ferrous sulfate (1 tablet/day) + one tablet of Claci-care multimineral-vitamin D containing 800 mg calcium, 200 mg magnesium, 8 mg zinc and 400 IU Vitamin D3 per day; group B received Ferrous sulfate (1 tablet/day) + 250 mg vitamin C + 55 mg vitamin E; and the controls received only one Ferrous sulfate tablet daily. Results: The incidence of preeclampsia in group A was significantly lower than the control group (p=0.03), while there was no significant difference between group B and controls (p=0.50), as well as groups A and B (p=0.063). The incidence of neonatal complications in the group A was significantly lower than the control group (p=0.01), while there was no significant difference between group B and control (p=0.48). Conclusion: According to the results, calcium, magnesium, and zinc supplements have a significant effect on the prevention of preeclampsia. In addition, prescription of multimineral-vitamin D during pregnancy can be a low-cost and affordable way to reduce the incidence of preeclampsia in women who are at high risk of preeclampsia.

Item Type: Article
Creators:
CreatorsEmail
Azami, M.UNSPECIFIED
Azadi, T.UNSPECIFIED
Farhang, S.UNSPECIFIED
Rahmati, S.UNSPECIFIED
Pourtaghi, K.UNSPECIFIED
Keywords: Prevention Preeclampsia Calcium Magnesium Zinc Vitamin D Vitamin C Vitamin E pregnant-women risk calcium hypertension diagnosis trial zinc Obstetrics & Gynecology
Divisions:
Page Range: pp. 273-278
Journal or Publication Title: International Journal of Reproductive Biomedicine
Journal Index: ISI
Volume: 15
Number: 5
ISSN: 2476-4108
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/308

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