Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Keratoconus indices and their determinants in healthy eyes of a rural population

Thu Apr 25 02:18:35 2024

(2019) Keratoconus indices and their determinants in healthy eyes of a rural population. Journal of Current Ophthalmology. ISSN 24522325 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Purpose: To determine the distribution of keratoconus indices in a 5–93-year-old healthy eyes of a rural population in Iran. Methods: In this cross-sectional study, multi-stage cluster sampling was applied to select subjects from two villages in the north and southwest of Iran. After obtaining informed consent, all subjects underwent ophthalmologic and optometric examinations. Corneal imaging by the Pentacam was done in subjects above 5 years between 9 a.m. and 2 p.m., at least 3 h after wakeup. All subjects who had abnormal keratoconus indices were excluded. Our main outcome was keratometry-flat (Kf), keratometry-steep (Ks), keratoconus index (KI), and central keratoconus index (CKI). Results: The mean ± SD of Kf, Ks, KI, and CKI was 43.12 ± 1.74, 44.25 ± 1.65, 1.02 ± 0.02, and 1.01 ± 0.01, respectively. According to multiple linear regression analysis, the mean index surface variance (ISV) (b: −1.367, P < 0.001), index vertical asymmetry (IVA) (b: −0.012, P < 0.001), KI (b: −0.011, P < 0.001), CKI (b: −0.001, P < 0.001), index height asymmetry (IHA) (b: −0.491, P: 0.005), and index height decentration (IHD) (b: −0.001, P < 0.001) were lower in men compared to women. Moreover, age had an indirect association with ISV (b: −0.030, P < 0.001) and average pachymetric progression index (RPIavg) (b: −0.001, P < 0.001), and a direct association with KI, CKI, and IHA. Spherical equivalence (SE) had an indirect association with KI (b: −0.001, P < 0.001) and RPIavg (b: −0.004, P < 0.001) and a direct association with CKI (b: 0.001, P < 0.001). Among all variables, sex had the greatest impact on ISV, IVA, KI, IHA, IHD, and minimum sagittal curvature (RSagMin). Conclusions: The Keratoconus indices of our study were similar to other studies. Although age, living place, and type of refractive error were associated with some indices, sex was the strongest determinant of Keratoconus indices in a population of healthy eyes. © 2019 Iranian Society of Ophthalmology

Item Type: Article
Creators:
CreatorsEmail
Hashemi, H.UNSPECIFIED
Pakzad, R.UNSPECIFIED
Heydarian, S.UNSPECIFIED
Yekta, A.UNSPECIFIED
Ostadimoghaddam, H.UNSPECIFIED
Mortazavi, M.UNSPECIFIED
Ramin, S.UNSPECIFIED
Khabazkhoob, M.UNSPECIFIED
Keywords: Anterior-surface indices Corneal tomography Iran Keratoconus indices Pentacam
Divisions:
Journal or Publication Title: Journal of Current Ophthalmology
Journal Index: Scopus
Identification Number: https://doi.org/10.1016/j.joco.2019.10.003
ISSN: 24522325 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/2903

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