Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Comparison of the effects of oral arnebia euchroma and oral ANGIPARS on wounds in diabetic rats

Sat Dec 10 01:58:24 2022

(2019) Comparison of the effects of oral arnebia euchroma and oral ANGIPARS on wounds in diabetic rats. International Journal of Pharmaceutical Research. pp. 120-123. ISSN 09752366 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Diabetic foot ulcer is one of the most common causes of amputation and imposes high social costs. The present study was conducted to evaluate the effect of oral arnebia euchroma extract on wounds in diabetic rats and was compared with oral and topical forms of ANGIPARS.Thirty diabetic male Wistar rats were categorized into different groups with similar wounds, and were treated with oral and topical forms of arnebia euchroma extract and ANGIPARS ointment and capsules, and were compared with each other and the control group. The clinical and statistical results indicate the superior effect of oral and topical forms of arnebia euchroma extract in comparison with oral and topical forms of ANGIPARS.The epithelial thickness(F (4.25) = 4189.10, p<0.01) and complete healing time(F (4.25) = 18.01, p<0.01), were respectively calculated. It is recommended that a human study be conducted to determine the level of blood glucose and its effect on TNFa and myeloperoxidase as the factors affecting tissue repair. © 2019, Advanced Scientific Research. All rights reserved.

Item Type: Article
Creators:
CreatorsEmail
Sharif, A.UNSPECIFIED
Shafiei, E.UNSPECIFIED
Hosseinzadeh, M.UNSPECIFIED
Keywords: ANGIPARS Arnebia euchroma Diabetic foot arnebia euchroma extract Melilotus extract myeloperoxidase plant extract unclassified drug wound healing promoting agent animal experiment animal model Article Borago comparative effectiveness controlled study epithelium extract granulation tissue male Melilotus officinalis microcapsule nonhuman ointment rat tissue repair topical treatment wound healing
Divisions:
Page Range: pp. 120-123
Journal or Publication Title: International Journal of Pharmaceutical Research
Journal Index: Scopus
Volume: 11
Number: 3
Identification Number: https://doi.org/10.31838/ijpr/2019.11.03.015
ISSN: 09752366 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/2884

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