Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Recovery of severely ill COVID-19 patients by intravenous immunoglobulin (IVIG) treatment: A case series

Mon Nov 28 15:43:10 2022

(2020) Recovery of severely ill COVID-19 patients by intravenous immunoglobulin (IVIG) treatment: A case series. Virology. pp. 1-5. ISSN 1096-0341 (Electronic) 0042-6822 (Linking)

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/32530808

Abstract

INTRODUCTION: During the recent months, COVID-19 has turned to a global crisis claiming high mortality and morbidity among populations. Despite the high prevalence of the disease, it has currently no definitive treatment. We here reported the effects of intravenous immunoglobulin (IVIG) administration in severely ill COVID-19 patients diagnosed based on PCR and radiology tests. CASE PRESENTATION: Five severely ill COVID-19 patients in whom standard treatments failed were administrated with IVIG which prevented the deterioration of clinical symptoms. All the patients were treated with high-dose IVIG (0.3-0.5 g/kg) for 5 consecutive days so that no patient would receive lower than 25 g of the drug. All the patients showed a desirable therapeutic response and were discharged from the hospital with a stable clinical condition after being recovered. CONCLUSION: Treatment with IVIG at the therapeutic dose of 0.3-0.5 g/kg can improve the clinical condition and O2 saturation and prevent the progression of pulmonary lesions in COVID-19 patients with severe symptoms in whom standard treatments have failed.

Item Type: Article
Creators:
CreatorsEmail
Mohtadi, N.UNSPECIFIED
Ghaysouri, A.UNSPECIFIED
Shirazi, S.UNSPECIFIED
Sara, AnsariUNSPECIFIED
Shafiee, E.UNSPECIFIED
Bastani, E.UNSPECIFIED
Kokhazadeh, T.UNSPECIFIED
Tavan, H.UNSPECIFIED
Keywords: Covid-19 Ivig Improvement of interest.
Divisions:
Page Range: pp. 1-5
Journal or Publication Title: Virology
Journal Index: Pubmed
Volume: 548
Identification Number: https://doi.org/10.1016/j.virol.2020.05.006
ISSN: 1096-0341 (Electronic) 0042-6822 (Linking)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/2785

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