Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

The Chemical composition and anti-mycobacterial activities of Trachyspermum copticum and Pelargonium graveolens essential oils

Thu Dec 8 05:36:24 2022

(2019) The Chemical composition and anti-mycobacterial activities of Trachyspermum copticum and Pelargonium graveolens essential oils. Recent patents on anti-infective drug discovery. ISSN 2212-4071 (Electronic) 1574-891X (Linking)

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/31657682

Abstract

BACKGROUND: Microbial resistance to antibiotics and their adverse effects related to these antibiotics are the matter of global public health in 21th century. Emergence of drug resistant strains has interested the scientists to find the new antimicrobial agents among the medicinal plant's essential oil. METHODS: Anti-mycobacterial effects of Trachyspermum copticum and Pelargonium graveolens essential oils were assessed against multi-drug resistant clinical strains of Mycobacterium tuberculosis, Mycobacterium kansasii, Mycobacterium fortuitum and standard strain of Mycobacterium tuberculosis H37Rv by a Broth micro-dilution method. Pelargonium graveolens plant named 'Narmada was invented by Kulkarni R.N et al. (Patent ID, USPP12425P2) and a formulation comprising thymol obtained from Trachyspermum is useful in the treatment of drug resistant bacterial infections (Patent ID, US6824795B2). The chemical composition of hydro-distilled essential oils was analyzed by GC and GC-MS. RESULTS: Minimum Inhibitory Concentration (MIC) values for T. copticum essential oil against tested isolates were ranged from 19.5.

Item Type: Article
Creators:
CreatorsEmail
Kardan-Yamchi, J.UNSPECIFIED
Mahboubi, M.UNSPECIFIED
Kazemian, H.UNSPECIFIED
Hamzelou, G.UNSPECIFIED
Feizabadi, M. M.UNSPECIFIED
Keywords: M. tuberculosis Pelargonium graveolens Trachyspermum copticum antimycobacterial activity chemical compositiTrachyspermum copticum chemical composition essential oil
Divisions:
Journal or Publication Title: Recent patents on anti-infective drug discovery
Journal Index: Pubmed
Identification Number: https://doi.org/10.2174/1574891X14666191028113321
ISSN: 2212-4071 (Electronic) 1574-891X (Linking)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/2775

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