Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Investigating the incidence rate and geographical distribution of congenital hypothyroidism among neonates in Isfahan province using geographic information system (GIS) between 2002 and 2015

Thu Aug 18 18:41:25 2022

(2020) Investigating the incidence rate and geographical distribution of congenital hypothyroidism among neonates in Isfahan province using geographic information system (GIS) between 2002 and 2015. Journal of Pediatric Endocrinology & Metabolism. pp. 35-45. ISSN 0334-018X

Full text not available from this repository.

Official URL: http://apps.webofknowledge.com/InboundService.do?F...

Abstract

Background: Congenital hypothyroidism (CH) is one of the main causes of mental retardation in neonates. The disease is associated with genetic, climatic and environmental factors. Accordingly, the present study was conducted to determine the incidence rate and correlation of geographic factors with CH in Isfahan province in order to explain the role of climatic factors in the incidence of disease in this province. Methods: This cross-sectional study was conducted to determine the incidence rate and geographical distribution of CH in neonates born in the Isfahan province from the beginning of 2002 to the end of 2015. To estimate the geographic distribution, the ArcGIS software (version 10.3) was used and to investigate the relationship between geographical factors and CH, the Poisson regression test and dispersion diagrams were used. Data analysis was done using the SPSS16 software. Results: According to the results of the screening of 1,006/101 neonates born in Isfahan, the mean incidence rate of CH in all infants was 2.3, and that in male and female infants was 2.39 and 2.2 per 1000 live births, respectively. There was a statistically significant correlation between the city of residence (p = 0.01), climatic conditions (p= 0.044), annual precipitation (p= 0.027), sunlight (p= 0.01) and CH. However, there was no significant relationship between the mean altitude above sea level (p = 0.6), land use (p=0.4) and relative humidity (p= 0.24). Conclusions: Based on the findings of this study, the incidence rate of CH in Isfahan province was higher than the average of the country. Moreover, among the geographical factors, climatic conditions, annual precipitation and sunlight were associated with CH.

Item Type: Article
Creators:
CreatorsEmail
Karimi, A.UNSPECIFIED
Hashemipour, M.UNSPECIFIED
Asadollahi, K.UNSPECIFIED
Daliri, S.UNSPECIFIED
Keywords: congenital hypothyroidism geographic distribution incidence Isfahan neonates screening-program prevalence permanent iran Endocrinology & Metabolism Pediatrics
Divisions:
Page Range: pp. 35-45
Journal or Publication Title: Journal of Pediatric Endocrinology & Metabolism
Journal Index: ISI
Volume: 33
Number: 1
Identification Number: https://doi.org/10.1515/jpem-2019-0181
ISSN: 0334-018X
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/2672

Actions (login required)

View Item View Item